Evidence map›Paper›PMID 40016502›Full record

ArticleScientific reports2025

Evaluation of magnetic resonance spectroscopy total sodium concentration measures, and associations with microstructure and physical impairment in cervical myelopathy.

Bhavana S Solanky, Ferran Prados, Carmen Tur, Francesco Grussu, Selma Al-Ahmad, Xixi Yang, Alessia Bianchi, Baris Kanber, Antonino Russo, Vittorio Russo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bhavana S SolankyNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Queen Square, London, WC1N 3BG, UK. b.solanky@ucl.ac.uk.
Ferran PradosHawkes Institute, Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
Carmen TurNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Queen Square, London, WC1N 3BG, UK.
Francesco GrussuNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Queen Square, London, WC1N 3BG, UK.
Selma Al-AhmadNational Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Xixi YangNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Queen Square, London, WC1N 3BG, UK.
Alessia BianchiNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Queen Square, London, WC1N 3BG, UK.
Baris KanberHawkes Institute, Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
Antonino RussoNational Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Vittorio RussoNational Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
David ChoiNational Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Jalesh N PanickerDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Claudia A M Gandini Wheeler-KingshottNMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Queen Square, London, WC1N 3BG, UK.

Funding

'la Caixa' Foundation 100010434MRC MR/S026088/1Multiple Sclerosis Society 175Rosetrees Trust PGL22/100041Wings for Life 169111
6 · The paper itself

Abstract

Spinal cord injury causes a cascade of physiological responses, which may trigger a subsequent neurotoxic increase in intracellular sodium. This can lead to neurodegeneration, both at and beyond the site of injury, causing clinical symptoms and loss of function. However, in vivo measurements of tissue sodium remain challenging. Here we utilise sodium magnetic resonance spectroscopy (

Indexed as

Cervical CordSodiumSpinal Cord DiseasesSpinal Cord InjuriesAdultAgedCase-Control StudiesCervical VertebraeFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedSodiumASIA scoreCervical myelopathyMacromolecular tissue volumeNODDISodium MRSSpinal cord

Identifiers

PMID40016502
PMCPMC11868613

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.