ArticleScientific reports2025
Safety and efficacy of a unique scleral flap in mitomycin C-augmented trabeculectomy over one year.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Three-year outcomes of two-stage intra-Tenon low-dose mitomycin C injection versus sponge application in trabeculectomy.BMJ open ophthalmology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study introduced a modified trabeculectomy method and compare its effectiveness and safety to prior studies. Twenty-seven glaucoma patients (32 eyes) underwent mitomycin C-augmented trabeculectomy with a unique scleral flap shape at Kaohsiung Veterans General Hospital. The IOP decreased significantly from baseline (28.80 ± 11.37 mm Hg) to postoperative day 1, week 1, week 2, week 4, week 6, month 3, month 6, and year 1 (range, 14.10 ± 5.90 to 17.80 ± 5.14 mm Hg; all p < 0.05). The antiglaucoma medication use also decreased significantly from baseline (n = 4.72 ± 1.25) to 1 year after trabeculectomy (n = 0.75 ± 1.37) (p < 0.001). No surgical failures or glaucoma reoperations occurred during follow-up. Early complications and interventions included bleb encapsulation (n = 3, 9.38%), bleb leaks (n = 3, 9.38%), and needling revision (n = 1, 3.13%). Late complications and interventions included bleb encapsulation (n = 2, 6.45%), needling (n = 5, 16.13%), and cataract extraction (n = 2, 6.45%). Our trabeculectomy method with a modified scleral flap shape has demonstrated comparable success rates and improved safety compared to existing techniques. However, as this is a retrospective study, further randomized controlled trials are needed to draw definitive conclusions regarding its superiority or comparability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.