Evidence map›Paper›PMID 40016301›Full record

ArticleLeukemia2025

CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents.

Tom Reuvekamp, Lok Lam Ngai, Daphne den Hartog, Jannemieke Carbaat-Ham, Mona M H E Fayed, Willemijn J Scholten, Tim R Mocking, Dana A Chitu, Thomas Pabst, Saskia K Klein and 11 more

Abstract read
In one paragraph

Article in Leukemia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Tom ReuvekampDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0001-1346-6606
Lok Lam NgaiDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-0969-3766
Daphne den HartogDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Jannemieke Carbaat-HamDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Mona M H E FayedDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Willemijn J ScholtenDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Tim R MockingDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9170-4131
Dana A ChituHemato Oncology Foundation for Adults in the Netherlands, Rotterdam, The Netherlands.
Thomas PabstDepartment of Oncology, University Hospital, Inselspital and University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-6055-5257
Saskia K KleinDepartment of Hematology, University Medical Center Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-8847-2704
Georg StussiDepartment of Hematology, Ospedale Regionale, Bellinzona, Switzerland.ORCID http://orcid.org/0000-0002-1667-0637
Laimonas GriskeviciusHematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santaros Klinikos, Vilnius University, Vilnius, Lithuania.
Dimitri BreemsDepartment of Hematology, Ziekenhuis Netwerk Antwerpen (ZNA), Antwerp, Belgium.
Danielle van Lammeren-VenemaDepartment of Hematology, Hagaziekenhuis, Den Haag, The Netherlands.
Rinske BoersmaDepartment of Hematology, Amphia Hospital, Breda, The Netherlands.
Gert J OssenkoppeleDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Arjan A van de LoosdrechtDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-8311-983X
Costa BachasDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-5983-6193
Gerwin HulsDepartment of Hematology, University Medical Center Groningen, Groningen, The Netherlands.
David C de LeeuwDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Jacqueline CloosDepartment of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. j.cloos@amsterdamumc.nl.ORCID http://orcid.org/0000-0001-9150-8026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40016301
PMCPMC11976276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.