Evidence map›Paper›PMID 40016272›Full record

ArticleScientific reports2025

Hepatic lipid metabolism is altered in Ubiad1

Ryoko Higa, Shirin Pourteymour, Pratibha S Kolan, Simon N Dankel, Johan Fernø, Gunnar Mellgren, Calvin Pan, Marcus M Seldin, Aldons J Lusis, Christian A Drevon and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ryoko HigaDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Sognsvannsveien 9, Domus Medica, 0372 Oslo, Norway.
Shirin PourteymourDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Sognsvannsveien 9, Domus Medica, 0372 Oslo, Norway.
Pratibha S KolanDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Sognsvannsveien 9, Domus Medica, 0372 Oslo, Norway.
Simon N DankelHormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
Johan FernøHormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
Gunnar MellgrenHormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
Calvin PanDepartment of Medicine, Division of Cardiology, University of California, 650 Charles E Young Drive South, Los Angeles, Los Angeles, CA, 90095, USA.
Marcus M SeldinDepartment of Biological Chemistry, University of California, Irvine, Irvine, USA.
Aldons J LusisDepartment of Medicine, Division of Cardiology, University of California, 650 Charles E Young Drive South, Los Angeles, Los Angeles, CA, 90095, USA.
Christian A DrevonDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Sognsvannsveien 9, Domus Medica, 0372 Oslo, Norway.
Knut T DalenDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Sognsvannsveien 9, Domus Medica, 0372 Oslo, Norway.
Frode A NorheimDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Sognsvannsveien 9, Domus Medica, 0372 Oslo, Norway. f.a.norheim@medisin.uio.no.

Funding

Researcher Exchange Program between Japan Society for the Promotion of Science and the Research Council of Norway FY 2022
6 · The paper itself

Abstract

UbiA prenyltransferase domain containing 1 (Ubiad1) has the potential to affect cholesterol and phospholipid levels in different cell types. We previously identified Ubiad1 as a candidate gene for regulating subcutaneous fat pad weight in a mouse genome-wide association study. Here we evaluated the relationship between Ubiad1 and obesity-related traits in cohorts of humans and mice, and in Ubiad1

Indexed as

DimethylallyltranstransferaseLipid MetabolismLiverAdipose TissueAnimalsDiet, High-FatFemaleHumansMaleMiceMice, Inbred C57BLMice, KnockoutObesitySex FactorsDimethylallyltranstransferaseHPLC-qTOF/MSLipid metabolismNAFLDRNA-seqSex differencesUbiad1

Identifiers

PMID40016272
PMCPMC11868635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.