Evidence map›Paper›PMID 40016235›Full record

Trial reportScientific reports2025

Virtual delivery of group-based cognitive behavioral therapy for autistic children and youth during the COVID-19 pandemic was acceptable, feasible, and effective.

Jessica Brian, Abbie Solish, Jonathan Leef, Jenny Nguyen, Laura Bickle, Robyn Budovitch, Victoria Chan, Brianne Drouillard, Ellen Drumm, Lisa Genore and 13 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04666493 (Adapting Anxiety Intervention for Youth With Autism for Rapid Response to COVID-19), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04666493 nacompletednot on this map

Adapting Anxiety Intervention for Youth With Autism for Rapid Response to COVID-19: A Research Project to Provide and Evaluate Virtual Mental Health Care

TypeinterventionalSponsorHolland Bloorview Kids Rehabilitation HospitalRan2020 to 2022Enrolled101ConditionsAutism Spectrum DisorderArmsCognitive behavior therapy (CBT), specifically using the Facing Your Fears (FYF) curriculum
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jessica BrianHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada. jbrian@hollandbloorview.ca.
Abbie SolishHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Jonathan LeefHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Jenny NguyenHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Laura BickleWaterloo District School Board, 51 Ardelt Ave, Kitchener, ON, N2C 2R5, Canada.
Robyn BudovitchChild Development Institute, 197 Euclid Ave, Toronto, ON, M6J 2J8, Canada.
Victoria ChanHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Brianne DrouillardHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Ellen DrummYork Region District School Board, 60 Wellington St, Aurora, ON, L4G 3G2, Canada.
Lisa GenoreHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Rianne Hastie AdamsHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Robin HermolinHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Nora KlemencicChild Development Institute, 197 Euclid Ave, Toronto, ON, M6J 2J8, Canada.
Maude LambertChildren's Hospital of Eastern Ontario, 40 Smyth Rd, Ottawa, ON, K1H 8L1, Canada.
Kristina LeeSunnybrook Hospital, 2075 Bayview Ave, Toronto, ON, M4G 0A2, Canada.
Janys LimLondon Health Sciences Centre, 800 Commissioners Rd. East, London, ON, N6A 5W9, Canada.
Kathleen Mak-FanWaterloo District School Board, 51 Ardelt Ave, Kitchener, ON, N2C 2R5, Canada.
Monica O'NeillHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Stephanie PriceMariani and Associates/Child and Community Resources, Caswell Dr, Sudbury, ON, P3E 2N8, Canada.
Melissa PyeSioux Lookout First Nations Health Authority, 61 Queen St., Sioux Lookout, ON, P8T 1B8, Canada.
Elizabeth SeleznevaHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Azin TaheriHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.
Evdokia AnagnostouHolland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd, Toronto, ON, M4G 1R8, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety challenges co-occur at a high rate in autistic children and youth (~ 50-79%), often with significant interference with daily functioning. Evidence-based interventions (e.g., cognitive behavioral therapy (CBT)-based approaches) are effective in treating anxiety disorders across populations. Facing your fears (FYF), a group-based CBT program modified for youth with ASD, yields positive outcomes in controlled research settings and community implementation, but access is constrained by limited system capacity and families' distance from specialized centers. COVID-19 spurred innovations in virtual delivery of care, generating possibilities for increased scalability of evidence-based treatments. This study investigated the feasibility, acceptability, and effectiveness of FYF when delivered virtually through a tertiary care hospital in Ontario. Data were collected over one year (N = 100 autistic children/youth aged 8-13 years and their caregivers). Significant improvements emerged in caregiver- and self-reported anxiety symptoms, and caregivers reported increased self-efficacy in supporting their child with their anxiety. Significant predictors of treatment response included youth baseline anxiety, level of adaptive functioning, ASD symptoms, and caregiver self-efficacy. Three COVID-related factors were small but significant contributors to the model. Virtual delivery of FYF is feasible and effective for treating elevated anxiety in autistic children/youth and may improve access.ClinicalTrials.gov identifier: NCT04666493.

Indexed as

Autistic DisorderCognitive Behavioral TherapyCOVID-19Psychotherapy, GroupAdolescentAnxietyCaregiversChildFeasibility StudiesFemaleHumansMaleOntarioPandemicsSARS-CoV-2Self EfficacyAnxietyAutismAutism spectrum disorderCaregiverCognitive behavioral therapyCommunityCOVID-19GroupImplementationInterventionMental healthVirtual care

Identifiers

PMID40016235
PMCPMC11868523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.