ArticleNature communications2025
Magnetically reshapable 3D multi-electrode arrays of liquid metals for electrophysiological analysis of brain organoids.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Real-time sensing-integrated organoid-on-a-chip platforms: Technological progress and emerging biomedical applications.Bioactive materials · 2026Review
- EGaIn-based liquid-metal electrodes for electronic interfaces and contact engineering.iScience · 2026Review
- Stem cell derived neural organoid approaches for neurological diseases.Neural regeneration research · 2026Article
- Three-dimensional microelectrode arrays forBiomedical engineering letters · 2026Review
- Epilepsy as a Multiscale Network Disorder: Integrating Precision Therapeutics and Emerging Experimental Platforms.Pharmaceutics · 2026Review
- Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Neural dynamics of temporal interference stimulation monitoring by soft liquid metal interfaces across neural systems.Nature communications · 2026Article
- Liquid Metals for Reconfigurable Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Reversible Thermoactuation Unlocks Minimally Invasive Implantation and Retrieval of Soft Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- AI-driven tripartite classification for optimizing wearable bioelectronics in depression management.Science advances · 2026Article
- Decoding triple negative breast cancer bone metastasis: from 3D bioprinted models to clinical translation.Journal of nanobiotechnology · 2026Review
- Conformable Microelectrode Arrays Integrated with a Scoop-Shaped Slide-Well for Dynamic Electrophysiological Profiling of Patient-Derived Cardiac Organoids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Spinal cord extracellular matrix hydrogel enhances organoid maturation and functional regeneration after spinal cord injury.Materials today. Bio · 2026Article
- Soft Neural Interfaces for Circuit-Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models.Advanced healthcare materials · 2026Article
- Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Multilayered microelectrode array for monitoring electrophysiological signals of 3d neural networks in cerebral organoid.Microsystems & nanoengineering · 2026Article
- The neuro-skeletal crosstalk: Mechanisms, clinical implications, and smart material interventions.Journal of orthopaedic translation · 2026Review
- Organoid Brain-Machine-Interface Devices for Central Nervous System Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Multi-Channel Neural Interface for Neural Recording and Neuromodulation.Small methods · 2026Review
- Up-and-down transformable embedded ink writing strategy for soft 3D architectures.Nature communications · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
To comprehend the volumetric neural connectivity of a brain organoid, it is crucial to monitor the spatiotemporal electrophysiological signals within the organoid, known as intra-organoid signals. However, previous methods risked damaging the three-dimensional (3D) cytoarchitecture of organoids, either through sectioning or inserting rigid needle-like electrodes. Also, the limited numbers of electrodes in fixed positions with non-adjustable electrode shapes were insufficient for examining the complex neural activity throughout the organoid. Herein, we present a magnetically reshapable 3D multi-electrode array (MEA) using direct printing of liquid metals for electrophysiological analysis of brain organoids. The adaptable distribution and the softness of these printed electrodes facilitate the spatiotemporal recording of intra-organoid signals. Furthermore, the unique capability to reshape these soft electrodes within the organoid using magnetic fields allows a single electrode in the MEA to record from multiple points, effectively increasing the recording site density without the need for additional electrodes.
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