Evidence map›Paper›PMID 40016188›Full record

ArticleBlood cancer journal2025

Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia.

Rishi S Kotecha, Sarah M Trinder, Anastasia M Hughes, Benjamin H Mullin, Sarah Rashid, Jinbo Yuan, Jiake Xu, Owen Duncan, Patrycja Skut, Grace-Alyssa Chua and 7 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rishi S KotechaLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.ORCID http://orcid.org/0000-0003-1836-4075
Sarah M TrinderDepartment of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia.
Anastasia M HughesLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Benjamin H MullinSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Sarah RashidSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Jinbo YuanSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Jiake XuSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Owen DuncanCentre for Microscopy, Characterisation and Analysis, University of Western Australia, Perth, WA, Australia.ORCID http://orcid.org/0000-0001-6999-1509
Patrycja SkutLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Grace-Alyssa ChuaLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Sajla SinghLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Joyce OommenLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Richard B LockChildren's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-3436-9071
Ursula R KeesLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Sebastien MalingeLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.ORCID http://orcid.org/0000-0002-9533-7778
Vincent KuekLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia.
Laurence C CheungLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, WA, Australia. l.cheung@curtin.edu.au.ORCID http://orcid.org/0000-0001-6298-5288

Funding

Department of Health | National Health and Medical Research Council (NHMRC) APP1142627Department of Health | National Health and Medical Research Council (NHMRC) APP1157871Department of Health | National Health and Medical Research Council (NHMRC) APP1163933Department of Health | National Health and Medical Research Council (NHMRC) APP2003629
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40016188
PMCPMC11868389

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.