Evidence map›Paper›PMID 40015937›Full record

ArticleJournal of Zhejiang University. Science. B2025

Effects of glyphosate, antibiotics, and an anticoccidial drug on pancreatic gene expression and blood physiology in broilers.

Georgi Yu Laptev, Daria G Tiurina, Elena A Yildirim, Elena P Gorfunkel, Larisa A Ilina, Valentina A Filippova, Andrei V Dubrovin, Alisa S Dubrovina, Evgeni A Brazhnik, Natalia I Novikova and 6 more

Abstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Genome-Wide Association Studies in Japanese Quails of the FInternational journal of molecular sciences · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Georgi Yu LaptevMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Daria G TiurinaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Elena A YildirimMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia. deniz@biotrof.ru.
Elena P GorfunkelMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Larisa A IlinaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Valentina A FilippovaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Andrei V DubrovinMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Alisa S DubrovinaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Evgeni A BrazhnikMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Natalia I NovikovaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Veronika K MelikidiMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Kseniya A SokolovaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Ekaterina S PonomarevaMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Vasiliy A ZaikinMolecular Genetics and Microbiomics Laboratory, BIOTROF+ Ltd., Pushkin, St. Petersburg 196602, Russia.
Darren K GriffinSchool of Natural Sciences, University of Kent, Canterbury, Kent, CT2 7NJ, UK.
Michael N RomanovFederal State Budgetary Educational Institution of Higher Education "St. Petersburg State Agrarian University," Pushkin, St. Petersburg 196605, Russia. deniz@biotrof.ru, m.romanov@kent.ac.uk.

Funding

the Russian Science Foundation 22-16-00128
6 · The paper itself

Abstract

Drugs and pesticide residues in broiler feed can compromise the therapeutic and production benefits of antibiotic (ANT) application and affect gene expression. In this study, we analyzed the expression of 13 key pancreatic genes and blood physiology parameters after administering one maximum residue limit of herbicide glyphosate (GLY), two ANTs, and one anticoccidial drug (AD). A total of 260 Ross 308 broilers aged 1‍-‍40 d were divided into the following four groups of 65 birds each: control group, which was fed the main diet (MD), and three experimental groups, which were fed MD supplemented with GLY, GLY+ANTs (enrofloxacin and colistin methanesulfonate), and GLY+AD (ammonium maduramicin), respectively. The results showed that the addition of GLY, GLY+ANTs, and GLY+AD caused significant changes in the expression of several genes of physiological and economic importance. In particular, genes related to inflammation and apoptosis (interleukin 6 (

Indexed as

Anti-Bacterial AgentsChickensGene ExpressionGlycinePancreasAnimal FeedAnimalsGlyphosateHerbicidesAnti-Bacterial AgentsGlycineGlyphosateHerbicidesAntibioticAnticoccidial drugBlood parameterBroilerGene expressionGlyphosatePancreas

Identifiers

PMID40015937
PMCPMC11867781

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.