Evidence map›Paper›PMID 40015924›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Development and Preclinical Evaluation of [

Xiaoyan Li, You Zhang, Jason C Mixdorf, Qianyun Wu, Sophia J Lee, Jonathan W Engle, Todd E Barnhart, Shannon C Kenney, Lixin Rui, Weijun Wei and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Evaluation of albumin-binding PD-L1-targeted VHH for PET imaging in colorectal cancer.American journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Review
  5. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaoyan LiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
You ZhangDepartment of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jason C MixdorfDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Qianyun WuDepartment of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Sophia J LeeDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Jonathan W EngleDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Todd E BarnhartDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Shannon C KenneyDepartment of Oncology, University of Wisconsin-Madison, Madison, Wisconsin.
Lixin RuiDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin; and.
Weijun WeiDepartment of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; wwei@shsmu.edu.cn wcai@uwhealth.org.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin; wwei@shsmu.edu.cn wcai@uwhealth.org.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

CD70 is an emerging biomarker for both solid tumors and hematologic malignancies, highlighting the urgent need for a molecular imaging tracer capable of visualizing CD70 with favorable pharmacokinetics.

Indexed as

AlbuminsCD27 LigandCopper RadioisotopesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingSingle-Domain AntibodiesAnimalsCell Line, TumorHumansMicePositron-Emission TomographyRadioactive TracersTissue Distribution1,4,7-triazacyclononane-N,N',N''-triacetic acidAlbuminsCD27 LigandCopper-64Copper RadioisotopesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingRadioactive TracersSingle-Domain Antibodies64CuABDalbumin-binding domainCD70immuno-PETlymphomas

Identifiers

PMID40015924
PMCPMC11960615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.