Evidence map›Paper›PMID 40015315›Full record

ArticleVox sanguinis2025

Influenza and COVID-19 vaccination in Canadian blood donors: A comparison across pre- and post-pandemic periods.

Sheila F O'Brien, Lori Osmond, Mindy Goldman, Steven J Drews

Abstract readComparative Study
In one paragraph

Article in Vox sanguinis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sheila F O'BrienEpidemiology & Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-5332-2789
Lori OsmondEpidemiology & Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.
Mindy GoldmanDonation and Policy Studies, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0001-9904-9952
Steven J DrewsMicrobiology, Canadian Blood Services, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0003-2519-1109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesSeasonal vaccinations reduce donor illness and appointment cancellations and ensure plasma products have antibodies to vaccine-directed strains. We aimed to describe donor influenza and COVID-19 vaccination history and compare this with the general population. MATERIALS AND

methodsTwo online donor surveys were carried out in 2021 and 2024. Donors were asked about demographics, influenza (2019/2020, 2020/2021 and 2023/2024 seasons) and COVID-19 (ever and 2023/2024 season) vaccination and reasons for vaccination choices. General population vaccination statistics were extracted from public reports. Percentages of donors receiving vaccination were calculated with 95% confidence intervals. Multiple logistic regression models were fitted with demographics as independent variables.

resultsIn survey 1, 4582 (30.4% response rate) donors completed a questionnaire; in survey 2, 6376 (21% response rate). More donors under age 65 received the influenza vaccine compared with the general population under age 65 (58% vs. 30% in 2019/2020, 63% vs. 28% in 2023/2024, p < 0.0001) and aged 65+ (81% vs. 70% in 2019/2020, 90% vs. 73% in 2023/2024, p < 0.0001). Fewer donors and the general population received the COVID-19 vaccine in 2023/2024 (under 65 45% vs. 39%; 65+ 76% vs. 67%, p < 0.0001). Most said they were vaccinated to prevent infection and protect others.

conclusionSeasonal vaccination rates are higher in older donors, consistent with public health recommendations. Blood donors are more likely to be vaccinated against seasonal influenza than the general population, but post-pandemic uptake of the COVID-19 booster vaccine was low, more similar to the general population.

Indexed as

Blood DonorsCOVID-19COVID-19 VaccinesInfluenza, HumanInfluenza VaccinesSARS-CoV-2VaccinationAdultAgedCanadaFemaleHumansMaleMiddle AgedPandemicsSurveys and QuestionnairesCOVID-19 VaccinesInfluenza Vaccinesblood donorsCOVID‐19influenzaSARS‐CoV‐2vaccination

Identifiers

PMID40015315
PMCPMC12116029

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.