Evidence map›Paper›PMID 40015252›Full record

Trial reportPsychotherapy and psychosomatics2025

Eye Movement Desensitization and Reprocessing with and without Dialectical Behavior Therapy for Posttraumatic Stress Disorder and Comorbid Borderline Personality Disorder Symptoms: A Randomized Controlled Trial.

Aishah Cecile Snoek, Arne van den End, Aartjan T F Beekman, Jack Dekker, Inga Aarts, Matthijs Blankers, Chris Vriend, Odile A van den Heuvel, Nick Lommerse, Kathleen Thomaes

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychotherapy and psychosomatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aishah Cecile SnoekAmsterdam UMC, Psychiatry, Amsterdam, The Netherlands.
Arne van den EndAmsterdam UMC, Psychiatry, Amsterdam, The Netherlands.
Aartjan T F BeekmanAmsterdam UMC, Psychiatry, Amsterdam, The Netherlands.
Jack DekkerArkin Mental Health Care, Amsterdam, The Netherlands.
Inga AartsSinai Centrum, Amstelveen, The Netherlands.
Matthijs BlankersArkin Mental Health Care, Amsterdam, The Netherlands.
Chris VriendAmsterdam UMC, Psychiatry, Amsterdam, The Netherlands.
Odile A van den HeuvelAmsterdam UMC, Psychiatry, Amsterdam, The Netherlands.
Nick LommerseArkin Mental Health Care, Amsterdam, The Netherlands.
Kathleen ThomaesAmsterdam UMC, Psychiatry, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionComorbidity between posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD) is prevalent. Despite evidence-based therapies, high rates of nonresponse and dropout persist. This study therefore aimed to examine whether the concurrent application of eye movement desensitization and reprocessing (EMDR) for PTSD and dialectical behavior therapy (DBT) for BPD yields better results than EMDR alone.

methodsPatients with a PTSD diagnosis and at least four BPD symptoms were randomly assigned to EMDR (n = 63) or concurrent EMDR-DBT (n = 61). Over 1 year, changes in PTSD symptoms were measured using the Clinician-Administered PTSD Scale for DSM-5. Secondary outcomes included BPD symptoms, global functioning, and quality of life.

resultsBoth treatments led to large reductions in PTSD symptoms, without significant differences after 1 year (p = 0.312, d = -0.23, 95% CI = -0.6, 0.1). Both treatments also yielded large and comparable reductions in BPD symptoms and improved quality of life. Global functioning improved only in the EMDR condition according to one measure (World Health Organization Disability Assessment Schedule 2.0), while the other measure (Outcome Questionnaire 45) showed improvements in both groups. Additionally, patients in the EMDR-DBT condition were twice as likely to drop out from EMDR treatment compared to those in the EMDR-only condition.

conclusionStand-alone EMDR demonstrated safety and efficacy in alleviating PTSD and BPD symptoms, as well as enhancing quality of life. These findings support the use of EMDR as a strong therapeutic option for patients with PTSD and comorbid BPD symptoms. Further research is needed to assess longer-term outcomes beyond 1 year.

Indexed as

Borderline Personality DisorderDialectical Behavior TherapyEye Movement Desensitization ReprocessingStress Disorders, Post-TraumaticAdultCombined Modality TherapyComorbidityFemaleHumansMaleMiddle AgedQuality of LifeTreatment OutcomeBorderline personality disorderPosttraumatic stress disorderTreatment

Identifiers

PMID40015252
PMCPMC12133105

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.