Evidence map›Paper›PMID 40014855›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Dispensability of extrinsic DnaA regulators in

Thias Oberg Boesen, Godefroid Charbon, Haochen Fu, Cara Jensen, Michael Sandler, Suckjoon Jun, Anders Løbner-Olesen

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Dispensability of extrinsic DnaA regulators inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thias Oberg Boesen *Department of Biology, University of Copenhagen, Copenhagen 2200, Denmark.
Godefroid Charbon *Department of Biology, University of Copenhagen, Copenhagen 2200, Denmark.ORCID 0000-0003-4792-1889
Haochen Fu *Department of Physics, University of California San Diego, La Jolla, CA 92093.ORCID 0009-0006-5419-2388
Cara JensenDepartment of Physics, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0001-5552-9436
Michael SandlerDepartment of Physics, University of California San Diego, La Jolla, CA 92093.
Suckjoon JunDepartment of Physics, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-0139-4297
Anders Løbner-OlesenDepartment of Biology, University of Copenhagen, Copenhagen 2200, Denmark.ORCID 0000-0002-0344-6417

Funding

Control of cellular resource allocation across biological scales in microorganismsR35GM139622 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JUN, SUCKJOON · 2021 to 2025
$2.3M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM139622NIGMS NIH HHS R35 GM139622NSF | BIO | Division of Molecular and Cellular Biosciences (MCB) 2016090
6 · The paper itself

Abstract

Investigating a long-standing conceptual question in bacterial physiology, we examine why DnaA, the bacterial master replication initiator protein, exists in both ATP and ADP forms, despite only the ATP form being essential for initiation. We engineered the Δ4

Indexed as

Bacterial ProteinsCell CycleDNA-Binding ProteinsEscherichia coliEscherichia coli ProteinsAdenosine DiphosphateAdenosine TriphosphateDNA ReplicationGene Expression Regulation, BacterialAdenosine DiphosphateAdenosine TriphosphateBacterial ProteinsDnaA protein, BacteriaDNA-Binding ProteinsEscherichia coli Proteinsbacterial physiologyDnaAquantitative biologyreplication initiation

Identifiers

PMID40014855
PMCPMC11331064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.