Evidence map›Paper›PMID 40014801›Full record

Observational studyAnesthesia and analgesia2025

Design and Staged Implementation of a Multidisciplinary Preoperative Anemia Clinic at a Tertiary Care Medical Center.

Ethan H Crispell, Claire E Cassianni, Jennifer M Burt, Jessica A Gonzalez, Jamie L Petsch, Andrew C Hanson, Kellie A Robbins, Ronald S Go, Juan A Crestanello, Adam K Jacob and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Anesthesia and analgesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ethan H CrispellFrom the Mayo Clinic Alix School of Medicine, Rochester, Minnesota.
Claire E CassianniFrom the Mayo Clinic Alix School of Medicine, Rochester, Minnesota.
Jennifer M BurtPatient Blood Management Program, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Jessica A GonzalezPatient Blood Management Program, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Jamie L PetschPatient Blood Management Program, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Andrew C HansonDepartment of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.
Kellie A RobbinsDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Ronald S GoDivision of Hematology, Department of General Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Juan A CrestanelloDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
Adam K JacobDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Daryl J KorPatient Blood Management Program, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
Matthew A WarnerPatient Blood Management Program, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.

Funding

Attenuation of Anemia for the Optimization of Post-Hospitalization Functional Recovery in Survivors of Critical IllnessK23HL153310 · NHLBI · MAYO CLINIC ROCHESTER · PI WARNER, MATTHEW A · 2021 to 2025
$909k
Mayo Clinic Kern Center for the Science of Health Care Delivery Practice Transformation Award K23HL153310NHLBI NIH HHS K23 HL153310
6 · The paper itself

Abstract

backgroundPreoperative anemia is common and associated with adverse outcomes in surgical patients. There is limited information to guide the design and implementation of preoperative anemia clinics (PAC), which represents a critical barrier to entry for many practices.

methodsThis is a descriptive observational study highlighting the design and implementation of a multidisciplinary PAC, including key steps in planning, stakeholder engagement, organizational structure, identification of target populations, establishing anemia treatments, information technology and electronic health record integration, provider training, and data infrastructure. Demographic and clinical characteristics, laboratory results, and anemia treatments for individuals evaluated in the PAC from November 4, 2019 through September 15, 2023 are enumerated. Patient-reported outcomes (PROs) assessing changes in anemia symptoms and well-being after surgery are evaluated for 2 subsets of patients (one before PAC implementation [pre-PAC], another after PAC implementation [post-PAC]), without formal statistical comparison given limited sample sizes.

resultsThe PAC was initiated as a multidisciplinary effort under support from a Mayo Clinic Practice Transformation Award in 2019, including broad representation from anesthesiology, surgery, and medical practices, along with institutional project management support (eg, project manager, information technologists, systems engineers). While initially limited to cardiac surgery patients, the PAC underwent planned incremental expansion to include other surgical services. Over the study period, 1188 PAC consultations across 1159 unique patients met eligibility criteria, with a median age of 66 (57-73) years and 58.1% women. The most common etiology of anemia was iron deficiency (69.1%) followed by anemia related to cancer (17.3%). Anemia-directed therapies were recommended in 1038 (87.4%) encounters, with 730 (70.3%) of those receiving recommended treatment preoperatively. Seven hundred nine (97.1%) treatments included intravenous iron and 146 (20.0%) included erythropoiesis-stimulating agents. Fifteen pre-PAC and 38 post-PAC implementation patients completed PROs. PAC implementation was accompanied by earlier resolution of anemia symptoms and less pronounced declines in postoperative well-being scores.

conclusionsThis report highlights the key steps for successful PAC implementation. Treatment is possible for most patients and may be accompanied by improvements in patient-important outcomes.

Indexed as

AnemiaPatient Care TeamPreoperative CareTertiary Care CentersAgedFemaleHumansMaleMiddle AgedPatient Reported Outcome Measures

Identifiers

PMID40014801
PMCPMC12353018

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.