ArticleChemistry & biodiversity2025
Chemical Composition and Synergistic Antimicrobial Effects of Essential Oils From Four Commonly Used Satureja Species in Combination With Two Conventional Antibiotics.
Article in Chemistry & biodiversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Essential Oils and Their Multifunctional Activities Against Pseudomonas aeruginosa: Current Evidence and Perspectives.MicrobiologyOpen · 2026Review
- Current Knowledge of the GenusPharmaceuticals (Basel, Switzerland) · 2026Review
- GC/MS Analysis, Cytotoxicity, and Antimicrobial Properties of Six Moroccan Essential Oils Traditionally Used for COVID-19 Prevention.Molecules (Basel, Switzerland) · 2025Article
- Effects ofInternational journal of molecular sciences · 2025Article
- Modulatory Effects ofPharmaceuticals (Basel, Switzerland) · 2025Article
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Authors and funding
4 authors.
Funding
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Abstract
The chemical composition and the antimicrobial potency of four Satureja essential oils (EOs), and their synergism with two antimicrobials have been investigated. Gas chromatography (GC) and GC/mass spectrometry analysis showed that S. alpina EO was predominated by pulegone (88.8%), while pulegone (38.6%) and menthone (30%) were the major constituents of S. calamintha EO. S. montana and S. hortensis EOs were dominated by carvacrol (50.8%-32.8%), γ-terpinene (18.5%-40.1%), and p-cymene (8.2%-7.3%), respectively. The antimicrobial activity showed that S. montana and S. hortensis EOs exhibited potent activity (minimal inhibitory concentration and minimum microbiocidal [bactericidal and candidacidal] concentrations = 0.07-4.46 mg/mL for bacteria, and 0.27-1.11 mg/mL for Candida). All EOs showed high synergism with gentamicin against bacteria (gains ranged between 4- and 512-fold). Interestingly, this synergism was pronounced against the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa. Regarding the association with amphotericin B, synergistic and additive effects were recorded depending on the strain tested.
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