Evidence map›Paper›PMID 40014659›Full record

ArticlePlant biotechnology journal2025

SPDC-HG: An accelerator of genomic hybrid breeding in maize.

Zhenliang Zhang, Xin Wang, Yuxiang Zhang, Kai Zhou, Guangning Yu, Wenyan Yang, Furong Li, Xiusheng Guan, Xuecai Zhang, Zefeng Yang and 2 more

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Achieving High-Density and Stress-Resilient Maize Breeding Via Germplasm Innovation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenliang Zhang *Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Xin Wang *Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Yuxiang Zhang *Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Kai ZhouKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Guangning YuKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Wenyan YangKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Furong LiKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Xiusheng GuanKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.
Xuecai ZhangInternational Maize and Wheat Improvement Center (CIMMYT), Texcoco, México.
Zefeng YangKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-3465-8594
Chenwu XuKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-1971-1086
Yang XuKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, College of Agriculture, Yangzhou University, Yangzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-6493-4916

Funding

Jiangsu Agriculture Science and Technology Innovation Fund CX(21)1003Jiangsu Agriculture Science and Technology Innovation Fund CX(24)3099National Natural Science Foundation of China 32061143030National Natural Science Foundation of China 32100448National Natural Science Foundation of China 32170636the Key Research and Development Program of Jiangsu Province BE2022343the National Key Research and Development Program of China 2022YFD1201804the National Key Research and Development Program of China 2023YFD1202200the Priority Academic Program Development of Jiangsu Higher Education Institutionsthe Seed Industry Revitalization Project of Jiangsu Province JBGS[2021]009
6 · The paper itself

Abstract

Integrating multiple modern breeding techniques in maize has always been challenging. This study aimed to address this issue by applying a flexible sparse partial diallel cross design composed of 945 maize hybrids derived from 266 inbred lines across different heterotic groups. The research integrated genome-wide association studies, genomic selection and genomic evaluation of parental inbred lines to accelerate the breeding process for developing single-cross hybrids. Significant associations were identified for 7-25 stable single nucleotide polymorphisms (SNPs) associated with the general combining abilities (GCAs) of nine yield-related traits. Using the maizeGDB and NCBI databases, 264 candidate genes were screened and functionally annotated based on significant SNPs detected by at least three statistical methods. The marker set developed from these GCA SNPs significantly improved the prediction accuracy of hybrids across all traits. The GCA estimates of the inbred lines involved in the top 100 and bottom 100 hybrids consistently ranked at the top and bottom, thereby confirming the accuracy of the predictions. Furthermore, the top 100 crosses selected using BayesB, GBLUP and LASSO showed a 105.4-108.6% increase in average ear weight compared to the bottom 100 crosses in field validation, demonstrating strong selection gains. Notably, amongst the top 100 hybrids, A017/A037 and A037/A169, each containing six superior genotypes were registered as Suyu 161 and Tongyu 1701, respectively, by the National Crop Variety Approval Committee in China. These results highlight the effectiveness of genomic selection and provide valuable insights for advancing genomic hybrid breeding in maize.

Indexed as

Genome, PlantPlant BreedingZea maysGenome-Wide Association StudyGenomicsHybridization, GeneticPolymorphism, Single Nucleotidegeneral combining abilitygenomic selectionhybrid breedingmaizesparse partial diallel cross design

Identifiers

PMID40014659
PMCPMC12018846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.