Evidence map›Paper›PMID 40014593›Full record

ArticlePloS one2025

Public attitudes to potential synthetic cells applications: Pragmatic support and ethical acceptance.

Olga Rook, Hub Zwart, Marileen Dogterom

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Olga RookDepartment of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands.ORCID 0009-0007-5157-5129
Hub ZwartErasmus School of Philosophy, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Marileen DogteromDepartment of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic cells constructed bottom-up represent a novel direction in Synthetic Biology. It has the potential to deepen the scientific understanding of life and, in the longer run, to open up new pathways for medical and environmental applications. Mapping preliminary public attitudes towards emerging technologies is an important step to further societal discussion and stakeholder participation. We conducted a vignette survey with nationally representative samples from 13 European countries (Czech Republic, France, Germany, Greece, Hungary, Italy, the Netherlands, Poland, Romania, Spain, Sweden, Turkey, and UK; N =  8,382) to explore public attitudes towards prospective synthetic cell technologies, such as anticancer therapy, CO2 emissions conversion to biofuel, and industrial waste recycling. Using data-driven techniques, we built a decision tree model of the factors affecting participants' attitudes and summarized the prevalent themes behind one's motivation. Our findings suggest substantial public support for prospective synthetic cell applications in the societally beneficial fields, most notably in healthcare.

Indexed as

AttitudePublic OpinionSynthetic BiologyAdultAgedEuropeFemaleHumansMaleMiddle AgedSurveys and Questionnaires

Identifiers

PMID40014593
PMCPMC11867391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.