Evidence map›Paper›PMID 40014574›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Understanding Nash epidemics.

Simon K Schnyder, John J Molina, Ryoichi Yamamoto, Matthew S Turner

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The theory of epidemics with altruism.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simon K SchnyderInstitute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan.ORCID 0000-0002-3529-1165
John J MolinaDepartment of Chemical Engineering, Kyoto University, Kyoto 615-8510, Japan.
Ryoichi YamamotoDepartment of Chemical Engineering, Kyoto University, Kyoto 615-8510, Japan.ORCID 0000-0002-8371-2833
Matthew S TurnerDepartment of Physics, University of Warwick, Coventry CV4 7AL, United Kingdom.

Funding

Japan Society for the Promotion of Science London (JSPS) 20H00129Japan Society for the Promotion of Science London (JSPS) 20H05619Japan Society for the Promotion of Science London (JSPS) 22H04841Japan Society for the Promotion of Science London (JSPS) 22K14012Japan Society for the Promotion of Science London (JSPS) 23H04508Japan Society for the Promotion of Science London (JSPS) JPJSCCA20230002Japan Society for the Promotion of Science London (JSPS) L19547Leverhulme Trust IAF-2019-019
6 · The paper itself

Abstract

Faced with a dangerous epidemic humans will spontaneously social distance to reduce their risk of infection at a socioeconomic cost. Compartmentalized epidemic models have been extended to include this endogenous decision making: Individuals choose their behavior to optimize a utility function, self-consistently giving rise to population behavior. Here, we study the properties of the resulting Nash equilibria, in which no member of the population can gain an advantage by unilaterally adopting different behavior. We leverage an analytic solution that yields fully time-dependent rational population behavior to obtain, 1) a simple relationship between rational social distancing behavior and the current number of infections; 2) scaling results for how the infection peak and number of total cases depend on the cost of contracting the disease; 3) characteristic infection costs that divide regimes of strong and weak behavioral response; 4) a closed form expression for the value of the utility. We discuss how these analytic results provide a deep and intuitive understanding of the disease dynamics, useful for both individuals and policymakers. In particular, the relationship between social distancing and infections represents a heuristic that could be communicated to the population to encourage, or "bootstrap," rational behavior.

Indexed as

EpidemicsCOVID-19HumansPhysical Distancingcontrol theoryepidemiologygame theorymathematical modelingmean-field games

Identifiers

PMID40014574
PMCPMC11892628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.