Evidence map›Paper›PMID 40014565›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Functional mapping of the molluscan brain guided by synchrotron X-ray tomography.

Michael Crossley, Anna Simon, Shashidhara Marathe, Christoph Rau, Arnd Roth, Vincenzo Marra, Kevin Staras

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Functional mapping of the molluscan brain guided by synchrotron X-ray tomography.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael CrossleyDepartment of Neuroscience, University of Sussex, Brighton BN1 9QG, United Kingdom.ORCID 0000-0002-3120-4124
Anna SimonWolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.
Shashidhara MaratheDiamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom.
Christoph RauDiamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom.
Arnd RothWolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.ORCID 0000-0003-0325-4287
Vincenzo MarraDepartment of Neuroscience, University of Sussex, Brighton BN1 9QG, United Kingdom.
Kevin StarasDepartment of Neuroscience, University of Sussex, Brighton BN1 9QG, United Kingdom.ORCID 0000-0003-4141-339X

Funding

Diamond Light Source (Diamond) MG34473Leverhulme Trust RPG-2024-041Sussex Neuroscience Seed Fund SNSF-24/1UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BBSRC/BB/V000233/1
6 · The paper itself

Abstract

Molluscan brains are composed of morphologically consistent and functionally interrogable neurons, offering rich opportunities for understanding how neural circuits drive behavior. Nonetheless, detailed component-level CNS maps are often lacking, total neuron numbers are unknown, and organizational principles remain poorly defined, limiting a full and systematic characterization of circuit operation. Here, we establish an accessible, generalizable approach, harnessing synchrotron X-ray tomography, to rapidly determine the three-dimensional structure of the multimillimeter-scale CNS of

Indexed as

BrainBrain MappingLymnaeaTomography, X-RayAnimalsNeuronsSynchrotronsbrainfeedingneural circuitsynchrotronX-ray tomography

Identifiers

PMID40014565
PMCPMC11892647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.