ArticlePloS one2025
Tailoring the surface pore morphology of bioceramic scaffolds through colloidal processing for bone tissue engineering.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, porous bioceramic scaffolds are developed with two materials, β-tricalcium phosphate (β-TCP) and hydroxyapatite (HA), with order of 10 micron-scale surface pores and approximately 40-60% volume porosity fabricated by soft templating of oil. Suitable oil and surfactant concentrations are determined for the creation of particle-stabilized emulsions with nearly spherical pores, as well as the capillary suspensions with elongated pores. The bioceramic scaffolds surfaces are then assessed for their ability to support osteoblast adhesion and growth, for applications as scaffolds for bone regeneration. The porous scaffolds' surfaces are compared to denser surfaces of the same material, where only submicron porosity arise from partial sintering, to interrogate the impact of surface topography on cell behavior. On the denser surfaces where no large pores are templated, β-TCP supports a larger number of osteoblasts compared to HA. Templated surface porosity significantly impacts the morphology and growth of the osteoblasts. Amongst the pore morphologies, the capillary suspension demonstrates enhanced biological function, whereas the emulsion performs the poorest. The β-TCP capillary suspension scaffold surface appears to provide the most favorable conditions for the osteoblasts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.