Evidence map›Paper›PMID 40014280›Full record

ArticleOral radiology2025

Development of a novel phantom for evaluating jawbone SPECT targeting medication-related osteonecrosis of the jaw.

Naoya Hayashi, Norikazu Matsutomo, Ryotaro Tokorodani, Mitsuha Fukami, Miki Nishimori, Hitomi Iwasa, Kie Nakatani, Tetsuya Yamamoto, Takuji Yamagami, Tomoaki Yamamoto

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Article in Oral radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Naoya HayashiDivision of Radiology, Department of Medical Technology, Kochi Medical School Hospital, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan. jm-n.hayashi@kochi-u.ac.jp.ORCID 0009-0003-1217-047X
Norikazu MatsutomoDepartment of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, B-524, 5-4-1 Shimorenjaku, Mitaka, Tokyo, 181-8612, Japan.
Ryotaro TokorodaniDivision of Radiology, Department of Medical Technology, Kochi Medical School Hospital, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan.
Mitsuha FukamiDepartment of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, B-524, 5-4-1 Shimorenjaku, Mitaka, Tokyo, 181-8612, Japan.
Miki NishimoriDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan.
Hitomi IwasaDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan.
Kie NakataniDepartment of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan.
Tetsuya YamamotoDepartment of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan.
Takuji YamagamiDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Kohasu, Oko-Cho, Nankoku, Kochi, 783-8505, Japan.
Tomoaki YamamotoDepartment of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, B-524, 5-4-1 Shimorenjaku, Mitaka, Tokyo, 181-8612, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe developed a new phantom for technical evaluation of jawbone single-photon emission computed tomography (SPECT) examinations for medication-related osteonecrosis of the jaw (MRONJ). In this study, we verified the utility of the phantom by determining optimal image reconstruction parameters.

methodsWe evaluated the image quality and quantification in jawbone SPECT images obtained by different reconstruction parameters using the phantom. The phantom images were acquired using a SPECT/computed tomography (CT) system and then reconstructed using ordered-subset expectation maximization (OSEM) iterative reconstruction with resolution recovery as well as scatter and attenuation correction with various update numbers and Gaussian filter full width at half maximums (FWHMs). The percent contrast (%contrast) and absolute recovery coefficient were calculated to determine the optimal reconstruction parameters (OSEM

resultsIn the phantom study, %contrast and absolute recovery coefficient increased with increasing update numbers. As the Gaussian filter FWHM increased, the quantitative accuracy and image sharpness decreased. The parameter determined by the phantom study (OSEM

conclusionsWe developed a novel phantom and adapted it for technical evaluation. This study demonstrated the utility of the developed phantom.

Indexed as

Bisphosphonate-Associated Osteonecrosis of the JawPhantoms, ImagingSingle Photon Emission Computed Tomography Computed TomographyTomography, Emission-Computed, Single-PhotonAgedAged, 80 and overFemaleHumansMaleMiddle AgedImage reconstructionJawboneMRONJPhantomSPECTSUV

Identifiers

PMID40014280
PMCPMC12167234

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