Evidence map›Paper›PMID 40014270›Full record

ArticleBehavior genetics2025

Are Depressive and Anxiety Symptoms Differentially Associated with Alcohol Use Behaviors: Multivariate Behavioral Genetic Analyses.

Tong Chen, Amanda M Ramos, Hermine H M Maes, Jennifer L Maggs, Jenae M Neiderhiser

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavior genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Shared genetic architecture and neurobiological pathways of problematic alcohol use and anxiety disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tong ChenDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA. toch9438@colorado.edu.
Amanda M RamosHuman Development and Family Studies, Utah State University, Logan, UT, USA.
Hermine H M MaesDepartment of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Jennifer L MaggsHuman Development and Family Studies, The Pennsylvania State University, University Park, PA, USA.
Jenae M NeiderhiserDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA.

Funding

PREVENTION AND METHODOLOGY TRAINING (PAMT)T32DA017629 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI Eric D Claus, Rina D Eiden · 2005 to 2026
$9.5M
Understanding the role of prenatal chemical exposure influences on child externalizing behaviors: Incorporating genetic influencesF32ES031832 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RAMOS, AMANDA MARIE · 2020 to 2023
$201k
NON-SHARED ENVIRONMENT IN ADOLESCENT DEVELOPMENTR01MH043373 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI REISS, DAVID · 1987 to 1991
–
NONSHARED ENVIRONMENT GENES AND ADOLESCENT MENTAL HEALTHR01MH048825 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI REISS, DAVID · 1991 to 1994
–
NIDA NIH HHS T32 DA017629NIEHS NIH HHS F32 ES031832NIMH NIH HHS R01 MH043373NIMH NIH HHS R01 MH048825
6 · The paper itself

Abstract

This study examined whether adolescent depressive and anxiety symptoms were differentially associated with alcohol use behaviors, and how these associations were explained by genetic, shared, and nonshared environmental influences. Participants were from the Nonshared Environment and Adolescent Development project of same-sex twin/sibling pairs from 720 families. Twin/sibling depressive and anxiety symptoms were measured by self-report at Time 1 (M

Indexed as

Alcohol DrinkingAnxietyDepressionAdolescentChildFemaleGene-Environment InteractionGenetics, BehavioralHumansMalePhenotypeYoung AdultAlcohol useAnxietyComorbidityDepressionGenetics

Identifiers

PMID40014270
PMCPMC12043400

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.