Computed tomographic pulmonary angiography using low tube voltage and slow contrast medium injection.

Keisuke Takiguchi, Atsushi Urikura, Tsukasa Yoshida, Kazuaki Nakashima, Koiku Asakura, Masahiro Endo

Abstract read

In one paragraph

Article in Emergency radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Reduced variability of pulmonary artery enhancement using a single-acquisition combined first-pass and inferior-vena-cava-derived second-pass contrast technique in CT pulmonary angiography.Emergency radiology · 2026
Article

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5 · Who and what money

Authors and funding

6 authors.

Keisuke TakiguchiDivision of Diagnostic Radiology, Shizuoka Cancer Center, Shimonagakubo, Nagaizumi, Sunto 1007, Shizuoka, 411-8777, Japan.

Atsushi UrikuraDepartment of Radiological Technology, Radiological Diagnosis, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. aurikura@ncc.go.jp.ORCID http://orcid.org/0000-0002-5799-0944

Tsukasa YoshidaDivision of Diagnostic Radiology, Shizuoka Cancer Center, Shimonagakubo, Nagaizumi, Sunto 1007, Shizuoka, 411-8777, Japan.

Kazuaki NakashimaDivision of Breast Imaging and Intervention, Shizuoka Cancer Center, Shimonagakubo, Nagaizumi, Sunto 1007, Shizuoka, 411-8777, Japan.ORCID http://orcid.org/0000-0002-1023-0454

Koiku AsakuraDivision of Diagnostic Radiology, Shizuoka Cancer Center, Shimonagakubo, Nagaizumi, Sunto 1007, Shizuoka, 411-8777, Japan.

Masahiro EndoDivision of Diagnostic Radiology, Shizuoka Cancer Center, Shimonagakubo, Nagaizumi, Sunto 1007, Shizuoka, 411-8777, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe diagnosis of acute pulmonary thromboembolism (PTE) is often performed by computed tomographic pulmonary angiography (CTPA). This study investigated the effects of a CTPA protocol combining slow contrast medium injection and low tube voltage on radiation exposure and image quality.

methodsWe retrospectively analyzed 82 patients undergoing CT scans for cancer treatment efficacy or follow-up, and simultaneous PTE exclusion. Patients were divided into two groups. Those in Group A (n = 43) received slow contrast injection (0.7-1.5 mL/s), and those in Group B (n = 39) received rapid injection (2.6-4.2 mL/s). All CT scans were performed using a multi-detector row CT scanner with optimized tube voltage and current settings. Contrast medium doses were adjusted based on the patient's body weight.

resultsGroup A had significantly lower radiation exposure compared with Group B. PTE was diagnosed in eight patients in Group A and seven in Group B, with no significant difference in prevalence rates. While Group B indicated higher mean CT values in the CTPA phase, the difference in the mean CT value of the pulmonary artery was only 29.6 Hounsfield units. Group A demonstrated superior contrast enhancement in parenchymal organs during the second phase.

conclusionThe slow-injection CTPA method proved effective for simultaneous PTE exclusion and cancer treatment evaluation, maintaining diagnostic accuracy with reduced risks associated with rapid injection.

Indexed as

Computed Tomography AngiographyContrast MediaPulmonary EmbolismAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRadiation DosageRetrospective StudiesContrast MediaAcute pulmonary thromboembolismCancer-associated thrombosisComputed tomography pulmonary angiographyLow tube voltageSlow injection

Identifiers

PMID40014248

DOI10.1007/s10140-025-02326-5

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.