Evidence map›Paper›PMID 40014206›Full record

SynthesisCell and tissue banking2025

Application of injectable platelet-rich fibrin (I-PRF) after posterior tooth removal surgery: a systematic review.

Ilan Hudson Gomes de Santana, Mayara Rebeca Martins Viana, Julliana Cariry Palhano Dias, Anderson Jara Ferreira, Eduardo Sant'Ana, Eduardo Dias Ribeiro

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Cell and tissue banking, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilan Hudson Gomes de SantanaHealth Sciences Center, Federal University of Paraíba (UFPB), João Pessoa, Paraíba, Brazil. ilan.hudson@academico.ufpb.br.
Mayara Rebeca Martins VianaHealth Sciences Center, Federal University of Paraíba (UFPB), João Pessoa, Paraíba, Brazil.
Julliana Cariry Palhano DiasHealth Sciences Center, Federal University of Paraíba (UFPB), João Pessoa, Paraíba, Brazil.
Anderson Jara FerreiraHealth Sciences Center, Federal University of Paraíba (UFPB), João Pessoa, Paraíba, Brazil.
Eduardo Sant'AnaUniversity of São Paulo (USP), São Paulo, Brazil.
Eduardo Dias RibeiroHealth Sciences Center, Federal University of Paraíba (UFPB), João Pessoa, Paraíba, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injectable platelet-rich fibrin (I-PRF) is primarily found in liquid form and plays a role in accelerating vascularization and aiding wound healing. To carry out a critical analysis of the therapeutic potential of injectable platelet-rich fibrin (I-PRF) in the postoperative management of these surgeries. The systematic review protocol for this study included start and end dates, research question, databases, PICO structure, search strategy, inclusion/exclusion criteria, types of studies, measures of effect, screening methods, data extraction/analysis and risk of bias assessment tools. Registered with PROSPERO (CRD42024537367), it guaranteed transparency and quality. Searches were carried out on the PubMed, Scopus, Embase, Wiley Online Library and Web of Science databases. Results: The systematic search in the databases identified 532 studies. After removing duplicates with Rayyan© software, 480 documents remained, of which 15 met the inclusion criteria. After evaluation following the review protocol, 5 studies were considered highly relevant and included in the systematic review. The results indicated not only uncomplicated healing and adequate osseointegration, but also a significant improvement in comfort parameters and post-operative recovery. It was observed that the application of I-PRF accelerated the healing process, reduced pain and edema, and improved soft and hard tissue regeneration.

Indexed as

Platelet-Rich FibrinTooth ExtractionHumansInjectionsWound HealingInjectable platelet-rich fibrin (I-PRF) and surgery oralMolarPostoperative periodTooth extraction

Identifiers

PMID40014206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.