Evidence map›Paper›PMID 40014087›Full record

ArticlePediatric cardiology2026

Early and Midterm Reintervention in Valve-Sparing Tetralogy of Fallot Repair: Role of Residual Lesion Score.

Javeria Tariq, Asefa Shariq Ansari, Akbar Mistry, Qalab Abbas, Waris Ahmad, Muneer Amanullah, Mahim Malik, Shazia Mohsin

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Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Javeria TariqDivision of cardiothoracic sciences, Sindh institute of urology and transplantation, Karachi, Pakistan.
Asefa Shariq AnsariClinical Research Cardiology Department, Tabba Heart Institute, Karachi, Pakistan.
Akbar MistryDivision of cardiothoracic sciences, Sindh institute of urology and transplantation, Karachi, Pakistan.
Qalab AbbasDepartment of Pediatric, Aga Khan University Hospital, Karachi, Pakistan.
Waris AhmadDepartment of Pediatric, Aga Khan University Hospital, Karachi, Pakistan.
Muneer AmanullahDivision of cardiothoracic sciences, Sindh institute of urology and transplantation, Karachi, Pakistan.
Mahim MalikRawalpindi Institute of Cardiology, Pediatric Cardiac Surgery, Rawalpindi, Pakistan.
Shazia MohsinDivision of cardiothoracic sciences, Sindh institute of urology and transplantation, Karachi, Pakistan. shzmhsn@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetralogy of Fallot (TOF) is a common congenital heart defect with a traditionally high reintervention rate of post-surgical correction. The Residual Lesion Score (RLS) is a tool used to evaluate the quality of surgical outcomes by assessing postoperative echocardiography findings and the need for unplanned reinterventions. The study assesses the association between the Residual Lesion Score (RLS) and early and midterm outcomes, including reintervention rates, in patients undergoing valve-sparing TOF repair at a tertiary care center in a low- and middle-income country (LMIC). We conducted a retrospective analysis of 62 patients who underwent valve-sparing TOF repair between January 2017 and December 2019 at Aga Khan University, Pakistan. The RLS was calculated based on postoperative echocardiograms and unplanned surgical or catheter-based reinterventions. Patients were categorized into RLS 1 (trivial or no residual lesions), RLS 2 (minor residual lesions), and RLS 3 (major residual lesions or reinterventions before discharge). Two (3.2%) patients lacked postoperative echocardiography, were assigned an RLS score of 5, and excluded from further analysis. Of the 60 patients, 13 (21%) had an RLS of 3, indicating major residual lesions, and 29 (48.3%) had an RLS of 2, indicating minor residual lesions. Early reinterventions were required in 11.7% of patients. Patients with RLS 3 had a significantly higher reintervention rate compared to those with RLS 2 (p = 0.003) reintervention and longer hospital stay (p-value = 0.3). Implementing RLS can help optimize postoperative management and patient outcomes by identifying patients at higher risk of early reintervention.

Indexed as

Cardiac Surgical ProceduresPostoperative ComplicationsReoperationTetralogy of FallotChildChild, PreschoolEchocardiographyFemaleHumansInfantMalePakistanRetrospective StudiesTime FactorsTreatment OutcomeLMICReinterventionResidual lesion scoreTOF Repair

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.