Evidence map›Paper›PMID 40014044›Full record

ReviewJournal of applied clinical medical physics2025

A review of artificial intelligence in brachytherapy.

Jingchu Chen, Richard L J Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang

Abstract readReview
In one paragraph

Review in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Trends in brachytherapy utilization in Canada from 2011 to 2020.Physics and imaging in radiation oncology · 2026
    Article
  3. Systematic review of artificial intelligence in brachytherapy.Journal of contemporary brachytherapy · 2026
    Review
  4. A review of artificial intelligence in brachytherapy.Journal of applied clinical medical physics · 2025
    Review
  5. Breakthroughs in modern brachytherapy are transforming cancer care.Physics and imaging in radiation oncology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jingchu ChenDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0009-0008-3021-9149
Richard L J QiuDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-7877-1900
Tonghe WangDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Shadab MominDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-1640-3643
Xiaofeng YangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-9023-5855

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Real-time Volumetric Imaging for Motion Management and Dose Delivery VerificationR01CA272991 · NCI · EMORY UNIVERSITY · PI Zhen Tian, Xiaofeng Yang · 2023 to 2026
$2.3M
Multiparametric MRI-guided Prostate HDR Brachytherapy with Focal Tumor BoostR01CA215718 · NCI · EMORY UNIVERSITY · PI YANG, XIAOFENG · 2018 to 2022
$1.8M
Intelligent and Personalized Online Adaptive Proton TherapyR01DE033512 · NIDCR · UNIVERSITY OF CHICAGO · PI Zhen Tian, Xiaofeng Yang · 2024 to 2026
$1.8M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA215718NCI NIH HHS R01 CA272991NIDCR NIH HHS R01 DE033512NIH HHS P30CA008748NIH HHS R01CA215718NIH HHS R01CA272991NIH HHS R01DE033512
6 · The paper itself

Abstract

Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy. We analyze AI's role in making brachytherapy treatments more personalized, efficient, and effective. The applications are systematically categorized into seven categories: imaging, preplanning, treatment planning, applicator reconstruction, quality assurance, outcome prediction, and real-time monitoring. Each major category is further subdivided based on cancer type or specific tasks, with detailed summaries of models, data sizes, and results presented in corresponding tables. Additionally, we discuss the limitations, challenges, and ethical concerns of current AI applications, along with perspectives on future directions. This review offers insights into the current advancements, challenges, and the impact of AI on treatment paradigms, encouraging further research to expand its clinical utility.

Indexed as

Artificial IntelligenceBrachytherapyMachine LearningNeoplasmsRadiotherapy Planning, Computer-AssistedDeep LearningHumansRadiotherapy DosageAIbrachytherapyHDRLDRmachine learning

Identifiers

PMID40014044
PMCPMC12148788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.