Evidence map›Paper›PMID 40013924›Full record

ArticleJournal of medical microbiology2025

Clinical metagenomics: ethical issues.

Tess Johnson, Euzebiusz Jamrozik, Prashanth Ramachandran, Stephanie Johnson

Abstract readCase ReportsEditorial
In one paragraph

Article in Journal of medical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tess JohnsonEthox Centre, Oxford Population Health, University of Oxford, Oxford, UK.
Euzebiusz JamrozikEthox Centre, Oxford Population Health, University of Oxford, Oxford, UK.
Prashanth RamachandranDepartment of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.
Stephanie JohnsonEthox Centre, Oxford Population Health, University of Oxford, Oxford, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Metagenomics is increasingly used for diagnosis in hospital settings. It is useful particularly in cases of unknown aetiology, where novel or difficult-to-diagnose pathogens are suspected, and/or following unexplained disease outbreaks. In this paper, we present three use cases that draw on existing reports: one involving a patient in intensive care with encephalitis of unknown aetiology; a second case with likely infection with drug-resistant

Indexed as

MetagenomicsChildFemaleHepatitisHumansKlebsiella InfectionsKlebsiella pneumoniaeMaleclinical ethicsdiagnosticELSImetagenomicsnext-generation sequencing

Identifiers

PMID40013924
PMCPMC11868657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.