Evidence map›Paper›PMID 40013841›Full record

ArticleACS synthetic biology2025

Toward Antibody Production in Genome-Minimized

Tobias Schilling, Rebekka Biedendieck, Rafael Moran-Torres, Mirva J Saaranen, Lloyd W Ruddock, Rolf Daniel, Jan Maarten van Dijl

Abstract read
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Development of Bacillus subtilis cell factories for nutraceuticals production.World journal of microbiology & biotechnology · 2026
    Review
  2. Article
  3. Review
  4. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tobias SchillingUniversity Medical Center Groningen, Department of Medical Microbiology, University of Groningen, Hanzeplein 1, P.O. Box 30001, 9700RB Groningen, The Netherlands.ORCID 0000-0002-6697-6319
Rebekka BiedendieckBraunschweig Centre of Systems Biology (BRICS) and Institute of Microbiology, Technische Universität Braunschweig, Rebenring 56, 38106 Braunschweig, Germany.ORCID 0000-0002-3567-6196
Rafael Moran-TorresTheoretical Biophysics, Humboldt-Universität zu Berlin, 10115 Berlin, Germany.
Mirva J SaaranenFaculty of Biochemistry and Molecular Medicine, Protein and Structural Biology Research Unit, University of Oulu, Aapistie 7B, 90220 Oulu, Finland.ORCID 0000-0003-3399-9415
Lloyd W RuddockFaculty of Biochemistry and Molecular Medicine, Protein and Structural Biology Research Unit, University of Oulu, Aapistie 7B, 90220 Oulu, Finland.
Rolf DanielInstitute of Microbiology and Genetics, Department of Genomic and Applied Microbiology, Georg-August-Universität Göttingen, Grisebachstr. 8, 37077 Göttingen, Germany.
Jan Maarten van DijlUniversity Medical Center Groningen, Department of Medical Microbiology, University of Groningen, Hanzeplein 1, P.O. Box 30001, 9700RB Groningen, The Netherlands.ORCID 0000-0002-5688-8438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacillus subtilisGenome, BacterialSingle-Chain AntibodiesBioreactorsHumansProtein FoldingRecombinant ProteinsRecombinant ProteinsSingle-Chain AntibodiesantibodyBacillus subtilisgenome reductionscFabscFvsecretion

Identifiers

PMID40013841
PMCPMC11934139

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.