Evidence map›Paper›PMID 40013593›Full record

ArticleRevista espanola de salud publica2025

[Health outcomes of deprescribing proton pump inhibitors: study protocol].

Amaya Echeverría Gorriti, Andrea Rodríguez Esquiroz, Patricia García González, Lorea Sanz Álvarez, Marta Marín Marín, Javier Gorricho Mendívil, Julen Fernández González, Mª Concepción Celaya Lecea, Ana Campillo Arregui, Rebeca Irisarri Garde and 1 more

Abstract readEnglish Abstract
In one paragraph

Article in Revista espanola de salud publica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amaya Echeverría GorritiSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Andrea Rodríguez EsquirozSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Patricia García GonzálezSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Lorea Sanz ÁlvarezSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Marta Marín MarínSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Javier Gorricho MendívilSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Julen Fernández GonzálezSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Mª Concepción Celaya LeceaSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Ana Campillo ArreguiSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Rebeca Irisarri GardeSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.
Javier Garjón ParraSubdirección de Farmacia y Prestaciones; Servicio Navarro de Salud-Osasunbidea. Pamplona. España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveProton pump inhibitors (PPI) are one of the groups of drugs with the highest prevalence of use. However, in many cases they are used for the treatment of unapproved indications. For this reason, in Navarra a strategy was implemented to deprescribe PPI in those cases in which their use was not indicated. Subsequently, a project was designed in order to analyze the health outcomes of that PPI deprescription strategy.

methodsA retrospective cohort study will be developed to evaluate health outcomes obtained after the implementation of the PPI deprescription strategy. The primary outcome will be the time until a serious adverse event, defined as one that causes hospital admission or death. We will analyze whether there are differences between patients who stopped PPI treatment and those who maintained it.

conclusionsIt is expected to obtain information on the health outcomes of the proton pump inhibitor deprescription strategy and information about the convenience of continuing it.

Indexed as

DeprescriptionsProton Pump InhibitorsHumansResearch DesignRetrospective StudiesProton Pump InhibitorsDeprescribingGastropathyProton pump inhibitorsSpain

Identifiers

PMID40013593
PMCPMC12131302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.