Evidence map›Paper›PMID 40013487›Full record

ArticleJournal of the American Chemical Society2025

An mRNA Display Approach for Covalent Targeting of a

Sijie Wang, Emily C Woods, Jeyun Jo, Jiyun Zhu, Althea Hansel-Harris, Matthew Holcomb, Manuel Llanos, Nichole J Pedowitz, Tulsi Upadhyay, John Bennett and 8 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Unique structural and ligand-binding properties of theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Imaging ofbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Unique structural and ligand binding properties of thebioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Sijie WangDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.
Emily C WoodsDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0003-3140-8458
Jeyun JoDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0002-6701-0452
Jiyun ZhuDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0002-8861-5450
Althea Hansel-HarrisDepartment of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0001-7064-1119
Matthew HolcombDepartment of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0002-8409-4344
Manuel LlanosDepartment of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California 92037, United States.
Nichole J PedowitzDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.
Tulsi UpadhyayDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0001-5547-8683
John BennettDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.
Matthias FellnerBiochemistry Department, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0003-3192-6984
Ki Wan ParkDepartment of Otolaryngology-Head & Neck Surgery Divisions, Stanford University School of Medicine, Stanford, California 94305, United States.
Anna ZhangDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.
Tulio A ValdezDepartment of Otolaryngology-Head & Neck Surgery Divisions, Stanford University School of Medicine, Stanford, California 94305, United States.
Stefano ForliDepartment of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0002-5964-7111
Alix I ChanDepartment of Peptide Therapeutics, Genentech, South San Francisco, California 94080, United States.ORCID 0000-0002-2698-4031
Christian N CunninghamDepartment of Peptide Therapeutics, Genentech, South San Francisco, California 94080, United States.
Matthew BogyoDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0003-3753-4412

Funding

AutoDock Suite: Next Generation Environment for Drug DesignR01GM069832 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI FORLI, STEFANO · 2004 to 2025
$10.9M
UC San Diego Medical Scientist Training ProgramT32GM154642 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Neil C Chi, Mary Kathleen Lewinski · 2025 to 2026
$2.9M
Staphylococcus serine hydrolases as targets for therapeutic and imaging contrast agentsR01EB026332 · NIBIB · STANFORD UNIVERSITY · PI BOGYO, MATTHEW · 2018 to 2021
$1.4M
NIBIB NIH HHS R01 EB026332NIGMS NIH HHS R01 GM069832NIGMS NIH HHS T32 GM154642
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

RNA, MessengerStaphylococcus aureusVirulence FactorsCatalytic DomainFluorescent DyesPeptides, CyclicFluorescent DyesPeptides, CyclicRNA, MessengerVirulence Factors

Identifiers

PMID40013487
PMCPMC12118155

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.