ArticleJournal of advanced veterinary and animal research2024
Understanding the skin blackening phenomenon in Youzhou Dark goats based on the histological characteristics of melanocytes.
Article in Journal of advanced veterinary and animal research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The study was conducted to identify the molecular mechanism of the phenotype formation of Youzhou black sheep by histological cytology and transcriptomics. Materials and Methods: In this study, HE and IHC staining were used to explore the patterns and cytological differences in skin pigment deposition between Youzhou Dark goats and Banjiao goats. In addition, the DEGs related to the black skin phenotype were identified via transcriptomic analyses. Finally, the expression pattern of the agouti signal protein (ASIP) gene in the skin from individuals with different skin color phenotypes was verified by FISH. Results: The results showed that compared with that on the skin surface of Banjiao goats, melanin deposition on the skin surface of Youzhou Dark goats was abnormally increased. The transcriptomic analyses showed that the expression of the Conclusion: The present study showed that a decrease in
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