Evidence map›Paper›PMID 40013261›Full record

ReviewHeliyon2025

Comparative study of mouse models of atopic dermatitis.

Siqi Ye, Lian Zhu, Tao Ruan, Jinjing Jia, Xiumei Mo, Fenggen Yan, Junfeng Liu, Yu Zhang, Dacan Chen

Abstract readReview
In one paragraph

Review in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Hyaluronic Acid ProfhiloMedicina (Kaunas, Lithuania) · 2026
    Article
  4. Article
  5. Chaga Mushroom (Journal of microbiology and biotechnology · 2026
    Article
  6. Article
  7. Anti-Inflammation and Anti-Hypersensitivity Effects ofPreventive nutrition and food science · 2025
    Article
  8. Article
  9. Review
  10. Protective Effect ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siqi YeState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Lian ZhuDepartment of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Tao RuanThe Second Clinical School of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Jinjing JiaState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Xiumei MoState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Fenggen YanState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Junfeng LiuState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Yu ZhangState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Dacan ChenState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic, recurrent inflammatory disease. Animal models are important for studying disease mechanisms and identifying new therapeutic agents. However, owing to AD heterogeneity and complexity, there is currently no mouse model that can fully simulate human AD. We searched experimental articles published between 2017 and 2021 to identify the most suitable AD mouse model. We summarized and compared 614 articles, including details on mouse strains, sex, age, irritants, modeling cycles, and spontaneous mouse models. BALB/c mice (45.3 %) were the most commonly used. Generally, 4-8-week-old mice were used, and 44 irritants were identified. The most common irritant was 2,4-dinitrochlorobenzene (DNCB), followed by

Indexed as

2,4-DinitrochlorobenzeneAtopic dermatitisMouse strainsMurine model

Identifiers

PMID40013261
PMCPMC11862492

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.