Evidence map›Paper›PMID 40013245›Full record

ArticleACS catalysis2025

Accessing Arenes via the Hydrodeoxygenation of Phenolic Derivatives Enabled by Hydrazine.

Benedetta Di Erasmo, Inna Perepichka, Hui Su, Luigi Vaccaro, Chao-Jun Li

Abstract read
In one paragraph

Article in ACS catalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benedetta Di ErasmoLaboratory of Green S.O.C. - Dipartimento di Chimica, Biologia e Biotecnologie, Università Degli Studi di Perugia, Via Elce di Sotto 8, Perugia 06123, Italy.
Inna PerepichkaDepartment of Chemistry, and FRQNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.
Hui SuDepartment of Chemistry, and FRQNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.ORCID https://orcid.org/0000-0002-2257-4342
Luigi VaccaroLaboratory of Green S.O.C. - Dipartimento di Chimica, Biologia e Biotecnologie, Università Degli Studi di Perugia, Via Elce di Sotto 8, Perugia 06123, Italy.ORCID https://orcid.org/0000-0003-4168-2303
Chao-Jun LiDepartment of Chemistry, and FRQNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.ORCID https://orcid.org/0000-0002-3859-8824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrodeoxygenation (HDO) is an effective method for converting lignin and its derived phenolic compounds to value-added aromatic chemicals and fuels. Efforts to exploit molecular hydrogen have been made to remove the hydroxyl group in lignin-derived phenolic compounds to make them appealing for the chemical industry. However, these processes rely on high pressure and expensive catalysts, presenting challenges in terms of safety, hydrogen storage, and cost-effectiveness. This highlights the demand for alternatives under more accessible reaction conditions. Herein, we present a methodology for the HDO of phenols and naphthols using Pd/C as a commercial heterogeneous catalyst employing hydrazine as a dual reagent for reducing and hydrazone formation. This paper presents an applicable substrate scope for the HDO of different naphthols and phenols including pharmaceutically relevant molecules such as paracetamol. Additionally, highly challenging steroid derivatives, such as β-estradiol, have been hydrodeoxygenated.

Identifiers

PMID40013245
PMCPMC11851789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.