ArticleCureus2025
Adrenal Hypoplasia: A Diagnostic and Clinical Challenge.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Multigenerational evidence of X-linked adrenal hypoplasia congenita due to a novel NR0B1 frameshift.Human genomics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adrenal insufficiency can be life-threatening and results from inadequate secretion of hormones by the adrenal cortex. In pediatric patients, the most common cause is congenital adrenal hyperplasia due to 21-hydroxylase deficiency. We present a clinical case of a 17-year-old male. During the neonatal period, he experienced a salt-wasting crisis with shock, hyponatremia, metabolic acidosis, and elevated adrenocorticotropic hormone (ACTH) levels, with normal 17-hydroxyprogesterone. Hydrocortisone and fludrocortisone were initiated. Ten months later, genetic testing for the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.