Evidence map›Paper›PMID 40013211›Full record

ArticleCureus2025

Pleural Effusion in a Patient With Chronic Myelomonocytic Leukemia Treated With Azacitidine.

Marwa Mir, Bella Gnakou, Akila Gill, Jia Yi Tan, Wajeeha Aiman, Hamid S Shaaban, Gunwant Guron

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marwa MirInternal Medicine, Saint Michael's Medical Center, Newark, USA.
Bella GnakouInternal Medicine, Morristown Medical Center, Morristown, USA.
Akila GillInternal Medicine, Saint Michael's Medical Center, Newark, USA.
Jia Yi TanInternal Medicine, Saint Michael's Medical Center, Newark, USA.
Wajeeha AimanInternal Medicine, Saint Michael's Medical Center, Newark, USA.
Hamid S ShaabanHematology and Oncology, Saint Michael's Medical Center, Newark, USA.
Gunwant GuronHematology and Oncology, Saint Michael's Medical Center, Newark, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleural effusion is an uncommon occurrence in chronic myelomonocytic leukemia (CMML) patients, and its mechanisms remain poorly understood. We report the case of a 66-year-old male with a known medical history of CMML, referred from the oncology clinic due to shortness of breath attributed to a left pleural effusion, evident on a chest X-ray following a chemotherapy session. A diagnostic thoracentesis and cytology were conducted, which yielded exudative fluid negative for malignant cells and found reactive mesothelial cells and macrophages in a background of numerous chronic inflammatory cells and acellular proteinaceous material. However, due to the limited effectiveness of cytological examination in identifying malignant pleural effusions, the occurrence of leukemic effusions in CMML patients may be underestimated. This case underscores the importance of prompt recognition and management of pleural effusion in patients with underlying hematologic conditions like CMML.

Indexed as

chronic myelomonocytic leukemia (cmml)extramedullary hematopoiesismyelodysplastic neoplasmpleural effusion treated with azacitidinetet2

Identifiers

PMID40013211
PMCPMC11859460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.