ArticleAnimal reproduction2025
Effects of exogenous GnRH administration at insemination on pregnancy rates of estrus-synchronized seven ewe populations during the breeding season.
Article in Animal reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Control of Estrus in Sheep: Protocol Architectures, Seasonal Effects, and Breed-Specific Reproductive Performance.Animals : an open access journal from MDPI · 2026Review
- Effects of phase-specific GnRH administration on ovarian functional markers, ovulation timing, and fertility in estrous-synchronized ewes.Frontiers in veterinary science · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to investigate the effects of GnRH at insemination on pregnancy and lambing in seven ewe populations during the breeding season. Estrus was synchronized in 1560 adult ewes using an intravaginal sponge impregnated with flurogestone acetate. The sponge was left in the vagina for 12 days followed by an injection of 330 IU of eCG at sponge removal. Each ewe was inseminated twice at 48 h and 60 h after sponge removal. The treatment group was intramuscularly injected at the first insemination with a dose of 16 μg GnRH and the control group with saline solution in each ewe population. The results showed that GnRH administration significantly decreased the pregnancy rate in three ewe populations, but had no effects in four ewe populations. Additionally, the litter size tended to increase in the treatment group compared to the control group in all seven ewe populations, but the difference was not significant. In conclusion, GnRH administration at insemination was not recommended for ewes undergoing a timed artificial insemination during the breeding season. The breed/population may be a critical determinant of the potential for exploiting GnRH application in sheep breeding programs.
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Registered trials
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