ArticleJournal of sickle cell disease2025
The role of religiosity and spirituality in coping with sickle cell disease clinical severity.
Article in Journal of sickle cell disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02156102 (Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers), which is not on this map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers
Who cites it
3 citing papers in PubMed.
- Preliminary Benefits of In-Home Virtual Reality for Chronic Pain in Sickle Cell Disease: Pilot Randomized Trial.Biomedicines · 2026Article
- Sickle cell pain: call for whole person health approaches to mechanisms-informed integrative management.Blood advances · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Objectives: Religiosity and spirituality often play a role in managing chronic diseases. Sickle cell disease (SCD) is a genetic chronic disease associated with lifelong complications, but there is limited analysis of the potential impact of religiosity and spirituality on SCD. This study aims to analyze the association between constructs of religiosity and spirituality with health outcomes (disease severity, depression, and pain) in an SCD population ( Methods: Data from the INSIGHTS Study (NCT02156102) were used for this analysis. The relationships between religious/spirituality measures (religious attendance, self-reported spirituality, religious saliency, coping, and support) and SCD outcomes (disease severity, depression, and pain scores) were analyzed through bivariate correlations and multivariable models. Models adjusted for different dimensions of religiosity and spirituality separately (Model 1) and all measures simultaneously (Model 2). Results: In the bivariate analyses, we found a positive association between disease severity and spirituality ( Conclusions: The observed associations between spirituality and disease severity among patients with SCD suggest that individuals with severe disease may beneficially use spirituality to cope with complications. Future research should rigorously evaluate this hypothesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.