Evidence map›Paper›PMID 40012916›Full record

ArticleOrganic process research & development2025

Scaling Up Gas-Liquid Photo-Oxidations in Flow Using Rotor-Stator Spinning Disc Reactors and a High-Intensity Light Source.

Arnab Chaudhuri, Wouter F C de Groot, Jasper H A Schuurmans, Stefan D A Zondag, Alessia Bianchi, Koen P L Kuijpers, Rémy Broersma, Amin Delparish, Matthieu Dorbec, John van der Schaaf and 1 more

Abstract read
In one paragraph

Article in Organic process research & development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arnab ChaudhuriDepartment of Chemical Engineering and Chemistry, Sustainable Process Engineering, University of Technology (TU/e), Eindhoven 5612 AZ, The Netherlands.
Wouter F C de GrootDepartment of Chemical Engineering and Chemistry, Sustainable Process Engineering, University of Technology (TU/e), Eindhoven 5612 AZ, The Netherlands.
Jasper H A SchuurmansFlow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), Universiteit van Amsterdam (UvA), Amsterdam 1098 XH, The Netherlands.
Stefan D A ZondagFlow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), Universiteit van Amsterdam (UvA), Amsterdam 1098 XH, The Netherlands.ORCID https://orcid.org/0000-0003-1463-4867
Alessia BianchiDepartment of Chemical Engineering and Chemistry, Sustainable Process Engineering, University of Technology (TU/e), Eindhoven 5612 AZ, The Netherlands.ORCID https://orcid.org/0009-0001-0520-1261
Koen P L KuijpersTechnology and Engineering Group, Janssen Research and Development, Turnhoutseweg 30, Beerse 2340, Belgium.
Rémy BroersmaSignify Research, Eindhoven 5656 AE, The Netherlands.
Amin DelparishDepartment of Chemical Engineering and Chemistry, Sustainable Process Engineering, University of Technology (TU/e), Eindhoven 5612 AZ, The Netherlands.
Matthieu DorbecTechnology and Engineering Group, Janssen Research and Development, Turnhoutseweg 30, Beerse 2340, Belgium.ORCID https://orcid.org/0000-0003-0808-9700
John van der SchaafDepartment of Chemical Engineering and Chemistry, Sustainable Process Engineering, University of Technology (TU/e), Eindhoven 5612 AZ, The Netherlands.ORCID https://orcid.org/0000-0002-2856-8592
Timothy NoëlFlow Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), Universiteit van Amsterdam (UvA), Amsterdam 1098 XH, The Netherlands.ORCID https://orcid.org/0000-0002-3107-6927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photochemical transformations have garnered renewed interest over the past decade for their ability to enable unique reactions under mild conditions. However, scaling up such processes, particularly in multiphase systems (e.g., gas-liquid), remains challenging. Previously, we demonstrated the potential of the photochemical rotor-stator spinning disc reactor (pRS-SDR) for scaling the photooxidation of α-terpinene to ascaridole, though the system was limited by the light source, resulting in suboptimal operation in a photon-limited regime. In this work, we unlock the full potential of the pRS-SDR by integrating a high-powered light source (up to 652 W optical output) specifically designed for the reactor. The results show that the high gas-liquid mass transfer rates achievable in the pRS-SDR allow for significant productivity improvements under high irradiance (16.3 kg day

Identifiers

PMID40012916
PMCPMC11852198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.