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ArticleVideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy2025

American Society for Gastrointestinal Endoscopy guideline on the diagnosis and management of GERD: methodology and review of evidence.

ASGE Standards of Practice Committee, Madhav Desai, Wenly Ruan, Nirav C Thosani, Manuel Amaris, J Stephen Scott, Ahmed Saeed, Barham Abu Dayyeh, Marcia Irene Canto, Wasif Abidi and 16 more

Abstract read
In one paragraph

Article in VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

ASGE Standards of Practice Committee
Madhav DesaiCenter for Interventional Gastroenterology at UTHealth, McGovern Medical School, Houston, Texas, USA.
Wenly RuanDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.
Nirav C ThosaniCenter for Interventional Gastroenterology at UTHealth, McGovern Medical School, Houston, Texas, USA.
Manuel AmarisDepartment of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida, USA.
J Stephen ScottBariatric & Metabolic Specialists, Overland Park, Kansas, USA.
Ahmed SaeedAdvanced Gastroenterology Associates, Overland Park, Kansas, USA.
Barham Abu DayyehDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Marcia Irene CantoDivision of Gastroenterology and Hepatology, The Johns Hopkins University, Baltimore, Maryland, USA.
Wasif AbidiDivision of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.
Omeed AlipourDivision of Gastroenterology, University of Washington Medical Center, Seattle, Washington, USA.
Stuart K AmateauDivision of Gastroenterology Hepatology and Nutrition, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.
Natalie CosgroveCenter for Interventional Endoscopy, AdventHealth, Orlando, Florida, USA.
Sherif E ElhanafiDivision of Gastroenterology, Texas Tech University Health Sciences Center, El Paso, Texas, USA.
Nauzer ForbesDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Divyanshoo R KohliPancreas and Liver Clinic, Providence Sacred Medical Center, Elon Floyd School of Medicine, Washington State University, Spokane, Washington, USA.
Richard S KwonDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Larissa L Fujii-LauDepartment of Gastroenterology, University of Hawaii, Honolulu, Hawaii, USA.
Jorge D MachicadoDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Neil B MaryaDivision of Gastroenterology and Hepatology, University of Massachusetts Medical Center, Worcester, Massachusetts, USA.
Saowanee NgamruengphongDivision of Gastroenterology and Hepatology, The Johns Hopkins University, Baltimore, Maryland, USA.
Swati PawaDepartment of Gastroenterology, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.
Sunil G ShethDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Nikhil R ThiruvengadamDivision of Gastroenterology and Hepatology, Loma Linda University, Loma Linda, California, USA.
Bashar J QumseyaDepartment of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida, USA.
ASGE Standards of Practice Committee Chair

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This clinical practice guideline from the American Society for Gastrointestinal Endoscopy (ASGE) provides an evidence-based approach for strategies to diagnose and manage GERD. This document was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework and serves as an update to the prior ASGE guideline on the role of endoscopy in the management of GERD (2014). The updated guideline addresses the indications for endoscopy in patients with GERD, including patients who have undergone sleeve gastrectomy (SG) and peroral endoscopic myotomy (POEM). It also discusses endoscopic evaluation of gastroesophageal junctional integrity comprehensively and uniformly. Important, this guideline discusses management strategies for GERD including lifestyle interventions, proton pump inhibitors (PPIs), and endoscopic antireflux therapy including transoral incisionless fundoplication (TIF), radiofrequency energy, and TIF combined with hiatal hernia repair (cTIF). The ASGE recommends upper endoscopy for the evaluation of GERD in patients with alarm symptoms. The ASGE suggests upper endoscopy for symptomatic patients with a history of SG and POEM. The ASGE recommends careful endoscopic evaluation, reporting, and photo-documentation of objective GERD findings and gastroesophageal junction landmarks and integrity to improve patient care and outcomes. In patients with GERD symptoms, the ASGE recommends lifestyle modifications. In patients with symptomatic and confirmed GERD with predominant heartburn symptoms, the ASGE recommends medical management including PPIs at the lowest dose for the shortest duration while initiating discussion about long-term management options. In patients with confirmed GERD with small hiatal hernia (≤2 cm) and Hill grade I or II flap valve who meet specific criteria, the ASGE suggests evaluation for TIF as an alternative to long-term medical management. In patients with confirmed GERD with a large hiatal hernia (>2 cm) and Hill grade 3 or 4 flap valve, the ASGE suggests evaluation for combined endoscopic-surgical TIF (cTIF) in a multidisciplinary review. This document clearly outlines the methodology, analysis, and decision used to reach the final recommendations and represents the official ASGE recommendations on the above topics.

Identifiers

PMID40012897
PMCPMC11852708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.