Evidence map›Paper›PMID 40012751›Full record

ArticleFrontiers in veterinary science2025

Exhaled propofol monitoring for plasma drug prediction in rats.

Xiaoxiao Li, Pan Chang, Xing Liu, Yi Kang, Zhongjun Zhao, Yixiang Duan, Wensheng Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoxiao Li *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Pan Chang *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Xing LiuDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Yi KangDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Zhongjun ZhaoSchool of Mechanical Engineering, Sichuan University, Chengdu, China.
Yixiang DuanSchool of Mechanical Engineering, Sichuan University, Chengdu, China.
Wensheng ZhangDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While propofol can be detected in exhaled breath in rats, robust evidence supporting its correlation with plasma concentrations or its use in predicting plasma levels remains lacking. In this study, eighteen mechanically ventilated rats were divided into three groups and injected with low (Group BL,

Indexed as

exhaled breathpharmacokineticspropofolratVUV-TOF MS

Identifiers

PMID40012751
PMCPMC11862916

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.