Evidence map›Paper›PMID 40012745›Full record

ArticleF1000Research2024

Evaluating the Efficacy of Gelatin-Chitosan-Tetraethyl Orthosilicate Calcium Hydroxide Composite as a Dental Pulp Medicament on  COX-2, PGP 9.5, TNF-α Expression and Neutrophil number.

Al-Qatta Ghadah Abdulrahman, Endytiastuti Endytiastuti, Retno Ardhani, Iwa Sutardjo Rus Sudarso, Bidhari Pidhatika, Mh Busra Fauzi, Heni Susilowati, Yulita Kristanti, Juni Handajani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Al-Qatta Ghadah AbdulrahmanStudent of Magister Dental Science Study Program, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.
Endytiastuti EndytiastutiStudent of Magister Clinical Dental Science Study Program, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.
Retno ArdhaniDepartment of Dental Biomedical Sciences, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.
Iwa Sutardjo Rus SudarsoMagister of Clinical Dental Science Study Program, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.
Bidhari PidhatikaResearch Center for Polymer Technology, National Research and Innovation Agency of the Republic of Indonesia, Jakarta, Indonesia.
Mh Busra FauziCenter of Tissue Engineering and Regenerative Medicine, Faculty of Medicine,, Universiti Kebangsaan Malaysia, Kuala Lumpur, 55281, Malaysia.ORCID https://orcid.org/0000-0001-6449-639X
Heni SusilowatiMagister of Dental Science Study Program, Faculty of Dentistry,, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0003-0808-7465
Yulita KristantiDepartment of Conservative Dentistry, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, 55281, Indonesia.
Juni HandajaniMagister of Dental Science Study Program, Faculty of Dentistry,, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-2102-6141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Calcium hydroxide (Ca(OH) Materials and methods: A total of 16 Wistar rat models of acute pulp injury were prepared and divided into two groups, treatment and control, 8 with each. In the treatment group, we applied a pulp-capping material using G-CH-TEOS-Ca (OH) Results: The results showed a decrease in COX-2 expression, but not significantly while PGP 9.5 and TNF-α expression were significantly higher than those in the control group. Neutrophil numbers were lower in the treatment group than in the control group, but the difference was not statistically significant. Conclusion: The G-CH-TEOS-Ca (OH)

Indexed as

Calcium HydroxideChitosanCyclooxygenase 2Dental PulpGelatinNeutrophilsSilicatesTumor Necrosis Factor-alphaAnimalsMaleRatsRats, WistarCalcium HydroxideChitosanCyclooxygenase 2GelatinPtgs2 protein, ratSilicatesTumor Necrosis Factor-alphaCalcium Hydroxide (Ca(OH)2)capping materialCOX-2Gelatin-Chitosan-Tetraethyl Orthosilicate-Calcium Hydroxide (G-CH-TEOS-Ca(OH)2) CompositeneutrophilsPGP 9.5TNF-α

Identifiers

PMID40012745
PMCPMC11862375

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.