Evidence map›Paper›PMID 40012711›Full record

ArticleFrontiers in psychiatry2025

Neuroscience-informed psychoeducation for addiction: a conceptual and feasibility study.

Tara Rezapour, Kayla L McLean, Elena Psederska, Khashayar Niki Maleki, Hamed Ekhtiari, Jasmin Vassileva

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07178158 (Enhancing Addiction Treatment Through Psychoeducation), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07178158 narecruitingnot on this mapstarted 2026, after this paper: background citation

Enhancing Addiction Treatment Through Psychoeducation: Evaluating the Feasibility and Acceptability of a Neuroscience-Informed Mobile App

TypeinterventionalSponsorVirginia Commonwealth UniversityRan2026 to 2027Enrolled40ConditionsSubstance Use DisordersArmsInstalling the Metacognium software app, Continue treatment as usual
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Longitudinal neurocognitive trajectories in a large cohort of youth who use cannabis: combining self-report and toxicology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tara RezapourInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, United States.
Kayla L McLeanInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, United States.
Elena PsederskaDepartment of Cognitive Science and Psychology, New Bulgarian University, Sofia, Bulgaria.
Khashayar Niki MalekiMetacognium LLC, Austin, TX, United States.
Hamed EkhtiariDepartment of Psychiatry, University of Minnesota, Minneapolis, MN, United States.
Jasmin VassilevaInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, United States.

Funding

Project 5 - Genetic architecture of alcohol use disorder using cross-trait genetic correlations and public next-generation sequencing studiesP50AA022537 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MICHAEL F MILES · 2014 to 2026
$19.6M
Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031990 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CLORE, JOHN N. · 2010 to 2011
$7.7M
Varieties of Impulsivity in Opiate and Stimulant UsersR01DA021421 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI VASSILEVA, JASMIN L · 2008 to 2025
$6.5M
An Alcohol Affected Sib Pair Study of Alcohol DependenceR37AA011408 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN · 2007 to 2016
$6.5M
Project 3: Cross Species Characterization of Gene Networks in Acute ResponsesP20AA017828 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN, MILES, MICHAEL F · 2009 to 2012
$2.2M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
Genetics, Romantic Relationships, and Alcohol Misuse in Emerging AdulthoodK01AA024152 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI SALVATORE, JESSICA E · 2016 to 2020
$741k
NCATS NIH HHS UM1 TR004360NCRR NIH HHS UL1 RR031990NIAAA NIH HHS K01 AA024152NIAAA NIH HHS K02 AA018755NIAAA NIH HHS P20 AA017828NIAAA NIH HHS P50 AA022537NIAAA NIH HHS R37 AA011408NIDA NIH HHS R01 DA021421
6 · The paper itself

Abstract

Over the past few decades, our understanding of substance use disorders (SUD) has been reshaped by evidence from neuroscience, which suggests that SUD are characterized by specific neuromarkers that transcend traditional diagnostic boundaries and act as pre-diagnostic markers that could be targeted through preventive attempts. Connectivity-based neuromarkers or brain networks have emerged as a promising framework, providing new insights into the neurocognitive mechanisms of SUD. Utilizing this data-driven framework assists prevention and intervention developers in offering a non-judgmental insight for adolescents regarding the potential vulnerability of neurocognitive systems to continued substance use. Given the importance of such awareness, this paper proposes a neural network-informed approach based on research domain criteria (RDoC) to characterize the content of neuroscience-informed psychoeducation designed for SUD. Furthermore, we argue that various features related to content and structure need to be considered when developing such interventions delivered through digital platforms (e.g., apps and websites). Finally, we introduce a theory-driven app called "NIPA", developed with the aim of increasing adolescents' awareness and resilience to the effects of drugs and other emotional triggers on brain and cognitive functions.

Indexed as

addictionadolescentsmetacogntiveneurocognitiveneuroscience-informed psychoeducationresearch domain criteria (RDoC)

Identifiers

PMID40012711
PMCPMC11862476

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.