Evidence map›Paper›PMID 40012600›Full record

ArticleBrain circulation

Moyamoya disease manifesting with bilateral involvement of the proximal vertebral arteries: A case report.

Omar Alwakaa, Felipe Ramirez-Velandia, Jean Filo, Michael Young, Christopher S Ogilvy, Justin H Granstein

Abstract readCase Reports
In one paragraph

Article in Brain circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Extracranial vascular association of moyamoya disease: a systematic review and machine learning analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Omar AlwakaaBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Felipe Ramirez-VelandiaBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Jean FiloBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Michael YoungBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Christopher S OgilvyBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Justin H GransteinBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moyamoya disease (MMD) is a cerebrovascular disorder characterized by progressive occlusion of intracranial arteries, often leading to stroke and intracerebral hemorrhage. While MMD classically affects the intracranial vasculature, we present an unusual case of bilateral vertebral steno-occlusion, resulting in vertebrobasilar insufficiency in a 37-year-old man with MMD and treated with angioplasty and stenting of the dominant vertebral artery. Review of the literature demonstrates proximal vertebral artery involvement to be a rare manifestation of moyamoya disease. This report contributes to the understanding of the clinical spectrum of MMD and emphasizes the need for vigilance and awareness of the possibility of extracranial vascular complications in affected individuals.

Indexed as

Extracranialischemic strokemoyamoya diseasestentingvertebral artery occlusionvertebrobasilar insufficiency

Identifiers

PMID40012600
PMCPMC11850940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.