Evidence map›Paper›PMID 40012560›Full record

Articlenpj biological physics and mechanics2025

Exploring effects of platelet contractility on the kinetics, thermodynamics, and mechanisms of fibrin clot contraction.

Evgenii Kliuchnikov, Alina D Peshkova, Minh Quan Vo, Kenneth A Marx, Rustem I Litvinov, John W Weisel, Prashant K Purohit, Valeri Barsegov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in npj biological physics and mechanics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evgenii KliuchnikovDepartment of Chemistry, University of Massachusetts, Lowell, MA USA.
Alina D PeshkovaDepartments of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA USA.
Minh Quan VoDepartment of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA USA.
Kenneth A MarxDepartment of Chemistry, University of Massachusetts, Lowell, MA USA.
Rustem I LitvinovDepartments of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA USA.
John W WeiselDepartments of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA USA.
Prashant K PurohitDepartment of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA USA.
Valeri BarsegovDepartment of Chemistry, University of Massachusetts, Lowell, MA USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms of blood clot contraction - platelet-driven fibrin network remodeling, are not fully understood. We developed a detailed computational

Indexed as

Biological physicsBiomaterialsComputational biophysics

Identifiers

PMID40012560
PMCPMC11850289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.