Evidence map›Paper›PMID 40012375›Full record

ArticleImmunology and cell biology2025

Notch dependent chromatin remodeling enables Gata3 binding and drives lineage specific CD8

Jessie O'Hara, Pushkar Dakle, Michelle Ly Thai Nguyen, Adele Barugahare, Taylah J Bennett, Vibha Av Udupa, Nicholas Murray, Gemma Schlegel, Constantine Kapouleas, Jasmine Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology and cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jessie O'HaraDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Pushkar DakleDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Michelle Ly Thai NguyenDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, Australia.
Adele BarugahareDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Taylah J BennettDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.ORCID https://orcid.org/0000-0003-0951-4609
Vibha Av UdupaDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Nicholas MurrayDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.ORCID https://orcid.org/0009-0001-1183-6423
Gemma SchlegelDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Constantine KapouleasDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Jasmine LiDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.
Stephen J TurnerDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.ORCID https://orcid.org/0000-0002-1002-0000
Brendan E RussDepartment of Microbiology, Monash Biomedical Institute, Monash University, Clayton, VIC, Australia.

Funding

Australian Research Council DP170102020National Health and Medical Research Council APP1003131
6 · The paper itself

Abstract

Activation of CD8

Indexed as

CD8-Positive T-LymphocytesCell LineageChromatin Assembly and DisassemblyGATA3 Transcription FactorReceptors, NotchAnimalsChromatinGranzymesImmunoglobulin J Recombination Signal Sequence-Binding ProteinInterleukin-4Lymphocyte ActivationMiceMice, Inbred C57BLProtein BindingSignal TransductionChromatinGata3 protein, mouseGATA3 Transcription FactorGranzymesImmunoglobulin J Recombination Signal Sequence-Binding ProteinInterleukin-4Rbpj protein, mouseReceptors, NotchCD8+ T cellGata3Granzymeinfluenza A virusNotchT cell memory

Identifiers

PMID40012375
PMCPMC11964803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.