Evidence map›Paper›PMID 40012186›Full record

ArticleThe American journal of case reports2025

Management of Post-Stroke Cold Sensations: A Case Study on Sympathetic Nerve Ablation.

Haojia Li, Dejian Chen, Jiajia Deng, Lu Sun, Jianjun Zhu, Hanrui Fan, Yingjie Hua, Xiaoyan Guo, Ming Yao, Yong Fei

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Haojia LiDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Dejian ChenDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Jiajia DengDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Lu SunSchool of Health Economics and Management, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Jianjun ZhuDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Hanrui FanDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.ORCID 0000-0003-2151-1099
Yingjie HuaDepartment of Pain Medicine, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Central Hospital, Lishui, Zhejiang, China.
Xiaoyan GuoDepartment of Radiology, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Ming YaoDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Yong FeiDepartment of Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Stroke is a leading cause of mortality worldwide and often results in complex sequelae. Peripheral circulation disorders in paralyzed limbs are particularly challenging, presenting as persistent cold sensations and cold-induced pain that severely impair patients' quality of life. This report presents an innovative approach to managing refractory post-stroke limb coldness and pain using computed tomography (CT)-guided sympathetic nerve radiofrequency ablation. CASE REPORT We present the case of a 65-year-old woman with hemiplegia in her left extremities following a cerebral infarction 1 year earlier. Despite standardized treatment, her condition worsened after 6 months, with increased spasticity, cold-induced pain, and a significant drop in temperature in the left limbs. To address these issues, CT-guided radiofrequency ablation of the sympathetic nerve at the fourth thoracic vertebra and the third lumbar vertebral body was performed at 75°C for 3 min. The procedure significantly improved the peripheral perfusion index, increased palm and foot temperature, and reduced pain. Magnetic resonance imaging revealed improved cerebral infarction and enhanced brain function in temperature-related regions. Ethical approval and patient consent for publication were obtained. CONCLUSIONS CT-guided radiofrequency ablation of the thoracic and lumbar sympathetic nerves effectively alleviates post-stroke peripheral circulation disorders, improves limb temperature, and enhances collateral circulation. This report underscores the importance of awareness and early intervention for such post-stroke complications in patients.

Indexed as

Catheter AblationCold TemperatureRadiofrequency AblationStrokeSympathectomyAgedFemaleHemiplegiaHumansTomography, X-Ray Computed

Identifiers

PMID40012186
PMCPMC11877399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.