ArticleRenal failure2025
Stress hyperglycemia ratio as an independent predictor of acute kidney injury in critically ill patients with acute myocardial infarction: a retrospective U.S. cohort study.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between stress hyperglycemia ratio and in-hospital mortality in acute myocardial infarction: a dose-response meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Integration of stress hyperglycemia ratio and c-reactive protein level improves postoperative acute kidney injury risk stratification after noncardiac surgery: A nested case-control study.Pakistan journal of medical sciences · 2026Article
- Early risk stratification of acute kidney injury severity in patients with acute myocardial infarction and diabetes using machine learning.Scientific reports · 2026Article
- Association between stress hyperglycemia ratio and all-cause mortality in neurocritical patients.Scientific reports · 2026Article
- Association between hemoglobin glycation index and mortality in critically ill patients with chronic obstructive pulmonary disease: a retrospective cohort study.European journal of medical research · 2026Article
- Article
- Predictive value of stress hyperglycemia ratio for the risk of heart failure during hospitalization in STEMI patients undergoing emergency percutaneous coronary intervention: a single-center retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Article
- Serum angiotensinogen as a biomarker for renal outcomes in patients with acute myocardial infarction: prognostic significance and clinical implications.BMC nephrology · 2025Observational
- Association between stress hyperglycemia ratio and all-cause mortality in patients with acute kidney injury: a retrospective analysis of the MIMIC-IV database using machine learning.BMC nephrology · 2025Article
- The Systemic Inflammation Response Index as an Independent Predictor of Acute Kidney Injury in Critically Ill Patients With Acute Myocardial Infarction: Insights From a Large-Scale Cohort Study.Mediators of inflammation · 2025Article
- Article
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9 authors.
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Abstract
backgroundAcute kidney injury (AKI) is a frequent and severe complication in critically ill patients with acute myocardial infarction (AMI), significantly worsening prognosis. Identifying early risk markers for AKI in AMI patients is critical for timely intervention. The stress hyperglycemia ratio (SHR), a marker of acute glycemic response to physiological stress, has been proposed as a predictor of AKI, but its role remains unclear.
objectiveThis study investigates the association between SHR and AKI development in critically ill patients with AMI, using data from the MIMIC-III and MIMIC-IV databases.
methodsA total of 4,663 critically ill AMI patients were analyzed. SHR was evaluated for its association with AKI incidence using logistic regression, restricted cubic splines, and mediation analysis. Subgroup and sensitivity analyses were performed to confirm robustness. Additionally, Cox regression and Kaplan-Meier survival analysis were used to explore SHR's association with in-hospital mortality in the overall cohort and AKI subgroup.
resultsHigher SHR levels were independently associated with an increased risk of AKI, demonstrating a J-shaped relationship. Mediation analysis revealed that neutrophil count and albumin partially mediated this effect. Kaplan-Meier survival curves showed significant differences in in-hospital mortality among SHR quartiles (log-rank
conclusionsSHR serves as an early and independent marker for AKI risk in critically ill AMI patients, offering potential utility in clinical risk stratification. However, its role in predicting in-hospital mortality appears limited. These findings underscore the importance of glycemic monitoring and management in AMI patients at risk of AKI.
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