ArticleEuropean journal of medical research2025
Clinical and laboratory characteristics of neurosyphilis: analysis of symptoms and risk factors.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Developing a multi-antigen fusion protein (Tp15-17-47) serological test to improve neurosyphilis diagnosis.BMC infectious diseases · 2026Article
- Demographic and laboratory characteristics of neurosyphilis: a retrospective cohort study from a tertiary dermatosis hospital.BMC infectious diseases · 2026Article
- Neurosyphilis and Parkinsonism: Overlapping Pathophysiology and Emerging Therapeutic Insights.Current neurovascular research · 2026Review
- Meningovascular Neurosyphilis Presenting as Multifocal Stroke: A Case Report and Literature Review.Cureus · 2026Article
- Quality and content analysis of syphilis-related short videos on Douyin (TikTok): A cross-sectional study.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study was conducted from 2021 to 2023 to analyze the clinical and laboratory characteristics of neurosyphilis and determine the risk factors associated with this condition.
methodsA total of 400 patients were enrolled, including 100 individuals diagnosed with neurosyphilis, 100 without neurosyphilis, 100 with latent syphilis, and 100 healthy control subjects. Comparative analysis methods, serum VDRL titration, and correlation analysis were employed during the study.
resultsThe analysis revealed significant differences in symptoms of central nervous system (CNS) involvement and serum VDRL titers among the patient groups. For instance, symptoms indicative of CNS impairment were more frequently observed in patients with neurosyphilis, and serum VDRL titers were statistically significantly higher in this same group.
conclusionsThe obtained results can be utilized in clinical practice to enhance the accuracy of neurosyphilis diagnosis and management, thereby contributing to the improvement of early detection of this condition and prevention of its complications. The study allows for the inference of the importance of early detection of (CNS) dysfunction symptoms in patients (neurosyphilis) with syphilis and identifies key factors influencing the development of this disease. The findings hold significance for the diagnosis and treatment of neurosyphilis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.