Evidence map›Paper›PMID 40011873›Full record

Trial reportBMC complementary medicine and therapies2025

Psychophysiological effects of music on sadness in participants with and without depressive symptoms.

Xuanyi Wang, Tian Lu, Bian Zhou, Wanlin Chen, Jing Zheng, Hang Chen, Shulin Chen

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06516666 (Psychophysiological Effects of Music on Sadness in Depressed and Non-Depressed Participants), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06516666 nacompletednot on this map

Psychophysiological Effects of Music on Sadness in Depressed and Non-Depressed Participants

TypeinterventionalSponsorZhejiang UniversityRan2023 to 2023Enrolled149ConditionsSadnessArmsMusic
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuanyi WangDepartment of Psychological and Behavioral Sciences, Zhejiang University, No 866 Yuhangtang Rd, Hangzhou, 310058, China.ORCID http://orcid.org/0000-0002-8645-5393
Tian LuCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China.
Bian ZhouDepartment of Psychological and Behavioral Sciences, Zhejiang University, No 866 Yuhangtang Rd, Hangzhou, 310058, China.
Wanlin ChenDepartment of Psychological and Behavioral Sciences, Zhejiang University, No 866 Yuhangtang Rd, Hangzhou, 310058, China.
Jing ZhengCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China.
Hang ChenCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China.
Shulin ChenDepartment of Psychological and Behavioral Sciences, Zhejiang University, No 866 Yuhangtang Rd, Hangzhou, 310058, China. chenshulin@zju.edu.cn.ORCID http://orcid.org/0000-0003-4114-3297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSadness can be a harbinger of serious medical conditions and a primary manifestation of depressive symptoms. Music is a promising modality for regulating sadness, although its effect on participants, whether with or without long-term depressive symptoms, remains unknown. In this study, the effect of music on sadness regulation was investigated using psychological and physiological indicators between depressed and non-depressed individuals.

methodsData were collected from 149 participants (18 to 29 years old). The participants were divided into two groups (depressed and non-depressed groups) based on their depressive symptoms, experienced sadness induction, and music intervention. Electrocardiogram signals were collected to measure heart rate variability (HRV).

results(1) Music alleviated sadness (increasing positive emotions, valence and dominance, while decreasing arousal); (2) sadness increased the duration between consecutive heartbeats, and music decreased this duration; (3) participants with depressive symptoms showed lower HRV than those without, and music enhanced HRV for the depressed group; (4) no significant difference in the effects of music was found between the two groups; and (5) the regulatory impact of music on sadness was not influenced by prior music listening habits.

conclusionsThe findings indicate that listening to music can be beneficial for both healthy and subclinical individuals when managing sadness. The findings underscore the importance of recognizing the role of music in promoting emotional well-being.

trial registrationThis trial was retrospectively registered on ClinicalTrials.gov PRS (Protocol Registration and Results System) (number NCT06516666) on July 22, 2024 ( https://register. CLINICALTRIALS: gov/ ).

Indexed as

DepressionMusicMusic TherapySadnessAdolescentAdultElectrocardiographyFemaleHeart RateHumansMaleYoung AdultDepressive symptomsEmotionHeart rate variabilityMusicSadness

Identifiers

PMID40011873
PMCPMC11863932

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.