Observational studyBMC pulmonary medicine2025
Relationship between lung consolidation size measured by ultrasound and outcome in ICU patients with respiratory failure.
Observational study in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05647967 (Evaluation of Regional Perfusion of Lung Consolidation Upon Lung Ultrasonography), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Regional Perfusion of Lung Consolidation Upon Lung Ultrasonography
Who cites it
1 citing paper in PubMed.
- Transesophageal lung ultrasound score is associated with arterial oxygenation and clinical outcomes in mechanically ventilated critically ill patients.Intensive care medicine experimental · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundLung ultrasound has been extensively used to assess the etiology of respiratory failure. Additionally, lung ultrasound-based scoring systems have been proposed to semi-quantify the loss of lung aeration in the ICU. The one most frequently used distinguishes four steps of progressive loss of aeration (scores from 0 to 3) and 3 scores mean tissue-like pattern. However, the burden of consolidation is not considered as tissue-like pattern is defined as 3 scores independently of its dimension. In this study, we present an ultrasound method for quantitative measurement of consolidation size and investigate the relationship between consolidation size and outcome in ICU patients with respiratory failure.
methodsA total of 124 patients in ICU were prospectively enrolled and 13 patients were excluded due to failure to obtain LUS measurements. Among the remaining 111 patients, 17 patients were non-intubated, and 94 patients under sedation and analgesia were intubated. All patients underwent lung ultrasound examination for the measurement of lung consolidation size between 24 and 48 h after ICU admission. Lung consolidation size was assessed by consolidation area index (CA), which was determined by tracing the maximum cross-sectional area of the region of consolidation. The Cox-regression model was constructed for 28- and 90-day mortality.
resultsConsolidation size was successfully evaluated in all patients. The CA was 24.2cm
conclusionsThe proposed CA parameter, determined by lung ultrasound, was readily accessible at the bedside. It is noteworthy that a larger CA was correlated with impaired oxygenation and increased mortality rates among ICU patients. Further investigation is required to establish the merits of incorporating CA into lung ultrasound assessments in the ICU.
trial registrationClinicalTrial.gov, Identifier NCT05647967, Date: Dec 13, 2022, retrospectively registered.
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