Evidence map›Paper›PMID 40011816›Full record

ArticleBMC pregnancy and childbirth2025

Prevalence and correlates of depressive and anxiety symptoms among pregnant women from an urban informal settlement in Nairobi, Kenya: a community-based cross-sectional study.

Stephen Mulupi, Amina Abubakar, Moses Kachama Nyongesa, Vibian Angwenyi, Margaret Kabue, Paul Murimi Mwangi, Rachel Odhiambo, Joyce Marangu, Eunice Njoroge, Mercy Moraa Mokaya and 8 more

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

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5citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

18 authors.

Stephen MulupiInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Amina AbubakarInstitute for Human Development, Aga Khan University, Nairobi, Kenya. amina.abubakar@aku.edu.
Moses Kachama NyongesaInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Vibian AngwenyiInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Margaret KabueInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Paul Murimi MwangiInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Rachel OdhiamboInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Joyce MaranguInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Eunice NjorogeInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Mercy Moraa MokayaInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Emmanuel Kepha ObulemireInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Eunice OmbechInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Derrick SsewanyanaAlliance for Human Development, Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada.
Greg MoranDepartment of Psychology, Western University, London, ON, Canada.
Marie-Claude MartinAlliance for Human Development, Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada.
Kerrie ProulxAlliance for Human Development, Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada.
Kofi MarfoInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Stephen LyeAlliance for Human Development, Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada.

Funding

International Development Research Centre (IDRC) and Aga Khan Foundation Canada (AKFC) Centre File: 108506-002
6 · The paper itself

Abstract

purposePrevious research, largely from the Global North, reports high rates of common mental health disorders among women in the antenatal period, but there is paucity of such data in contexts like Kenya. This study investigated the prevalence and correlates of depressive and anxiety symptoms among pregnant women in an urban informal settlement in Kenya's capital - Nairobi.

methodsAn analysis of baseline cross-sectional data from a pilot cluster randomized trial of an integrated early childhood development programme. Participants were pregnant women in their third pregnancy trimester (N = 249), residing in an urban informal settlement in Nairobi County. Mental health measures [(Patient health questionnaire (PHQ-9) and generalized anxiety disorder scale (GAD-7)] were administered alongside other sociodemographic, pregnancy, and health-related questionnaires. Linear regression analysis was performed to investigate correlates of antenatal depressive and anxiety symptoms.

resultsParticipant's mean age was 27.5 years (SD = 5.6). The prevalence of antenatal depressive and anxiety symptoms was 26.9% (95%CI: 21.4-32.4) and 6.4% (95%CI: 3.4-9.4), based on the PHQ-9 and GAD-7 cut-off scores of ≥ 10 respectively. Being married was a significant correlate for decreased depressive and anxiety symptoms. Higher levels of education (secondary or tertiary), history of three or more previous pregnancies, and an experience of moderate-to-extreme pain were significant correlates for elevated depressive symptoms. Similarly, tertiary level of education, history of four or more previous pregnancies, and experiencing pain were significant correlates for elevated anxiety symptoms for the pregnant women. Participants reporting feeling unwell had significantly higher anxiety symptom scores.

conclusionIn this setting, correlates of antenatal depressive and anxiety symptoms cut across demographic, pregnancy and health-related factors with implications for targeted interventions. Findings point to the need for screening of depression and anxiety as part of routine antenatal care. Further research is needed to understand these contextual correlates.

trial registrationThis study was part of the integrated early childhood development pilot cluster randomised control trial, retrospectively registered in the Pan African Clinical Trial Registry on 26/03/2021, registration number PACTR202103514565914.

Indexed as

AnxietyDepressionPregnancy ComplicationsPregnant PeopleAdultCross-Sectional StudiesFemaleHumansKenyaPilot ProjectsPregnancyPrevalenceUrban PopulationYoung AdultAntenatal mental healthAnxietyDepressive symptomsKenyaPregnancyUrban informal settlements

Identifiers

PMID40011816
PMCPMC11863928

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.